Thioctic Acid Impurity 21 CAS 137314-40-0
| CAS No. | 137314-40-0 |
| Molecular Formula | C8H14O2S2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Thioctic Acid Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Thioctic Acid Impurity 21 (CAS 137314-40-0), a pharmacopoeial impurity reference standard (molecular formula C8H14O2S2C4H11NO3, MW 327.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, Thioctic Acid Impurity 21 is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 327.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H14O2S2 C4H11NO3 |
| Molecular Weight | 327.45 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Thioctic Standards
- Thioctic acid Impurity 93 (CAS 102561-84-2)
- Thioctic acid impurity 60 (CAS 105484-55-7)
- Thioctic acid Impurity 79 (CAS 105986-59-2)
- Thioctic Acid Impurity 8 (CAS 1070-65-1)
- Thioctic Acid Impurity 11 (CAS 1071-71-2)
- Thioctic acid (CAS 1077-28-7)
- Thioctic acid Impurity 2 (CAS 108015-78-7)
- Thioctic acid Impurity 6 (CAS 108841-56-1)
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- D-Thr7-Tirzepatide (CAS CATO-CPTD788924)
Why CATO?
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