Thioctic acid Impurity 79 CAS 105986-59-2

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.105986-59-2
Molecular FormulaC12H22O2
Molecular Weight198.30 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Thioctic acid Impurity 79 CAS 105986-59-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Thioctic acid Impurity 79.

CATO supplies Thioctic acid Impurity 79 (CAS 105986-59-2), a pharmacopoeial impurity reference standard (molecular formula C12H22O2, MW 198.30 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Thioctic acid Impurity 79 (C12H22O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Thioctic acid Impurity 79 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H22O2
Molecular Weight198.30 g/mol
Purity≥95%
StorageStore at 2-8°C
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityStable under recommended storage conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1987

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