Dapagliflozin Impurity 1 CAS 1373321-04-0
| CAS No. | 1373321-04-0 |
| Molecular Formula | C21H25ClO6 |
| Molecular Weight | 408.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Dapagliflozin Impurity 1 (CAS 1373321-04-0), a pharmacopoeial impurity reference standard (molecular formula C21H25ClO6, MW 408.87 g/mol) used for the identification and quantification of trace impurities in APIs.
Dapagliflozin Impurity 1 (C21H25ClO6) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Dapagliflozin Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H25ClO6 |
| Molecular Weight | 408.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
Related Dapagliflozin Standards
- Dapagliflozin Furanose Isomer (CAS 1469910-70-0)
- Dapagliflozin Impurity N9 (CAS 2452300-81-9)
- Dapagliflozin (CAS 461432-26-8)
- Dapagliflozin Impurity 126 (CAS CATO-C4X-1138126)
- Dapagliflozin Impurity 144 (CAS 1408245-02-2)
- Dapagliflozin Impurity 15 (CAS CATO-C4X-113815)
- Dapagliflozin Impurity 152 (CAS 2459303-35-4)
- Dapagliflozin Impurity 2 (CAS 2271248-78-1)
Recommended Standards
- 2-Bromo-5-iodophenylboronic acid pinacol ester (CAS 2121512-32-9)
- 2-(3-Bromo-5-iodophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 942069-57-0)
- 1,1,1,9,9,9-Hexamethyl-3,5,7-trioctyl-3,5,7-tris((trimethylsilyl)oxy)pentasiloxane (CAS 187593-69-7)
- 1,1,1,5,5,5-Hexamethyl-3-octyl-3-((trimethylsilyl)oxy)trisiloxane (CAS 187592-85-4)
- Tazobactam EP Impurity B (CAS 120701-87-3)
- Cycloserine Impurity 5 HCl (CAS 112346-82-4)
- Naproxen EP Impurity N (CAS 5111-65-9)
- (E)-1-Hydroxy-3-methyl-2-octen-6-yne (CAS 102699-81-0)
- Methyl 3-methoxy-5-[4-(methylsulfanyl)phenyl]benzoate (CAS 1820609-17-3)
- 2,6-Difluoro-4-nitrobenzene-1-sulfonyl chloride (CAS 1193388-31-6)
- 1-(3-Methylpyrazin-2-yl)piperidin-3-ol (CAS 1289388-25-5)
- 2-Amino-1-(1h-pyrrol-2-yl)ethan-1-one (CAS 861591-86-8)
- 2-Propenoic acid, 2-methyl-, polymer with butyl 2-methyl-2-propenoate, ethenylbenzene and 1,2-propanediol mono(2-methyl-2-propenoate) (CAS 9072-88-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com