Dapagliflozin Impurity N9 CAS 2452300-81-9
| CAS No. | 2452300-81-9 |
| Molecular Formula | C21H25ClO6 |
| Molecular Weight | 408.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dapagliflozin Impurity N9 (CAS 2452300-81-9) is a certified pharmaceutical impurity reference standard with the molecular formula C21H25ClO6 and a molecular weight of 408.87 g/mol.
Based on its molecular formula C21H25ClO6, Dapagliflozin Impurity N9 contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 408.87 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dapagliflozin Impurity N9 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H25ClO6 |
| Molecular Weight | 408.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
Related Dapagliflozin Standards
- Dapagliflozin Furanose Isomer (CAS 1469910-70-0)
- Dapagliflozin (CAS 461432-26-8)
- Dapagliflozin Impurity 1 (CAS 1373321-04-0)
- Dapagliflozin Impurity 126 (CAS CATO-C4X-1138126)
- Dapagliflozin Impurity 144 (CAS 1408245-02-2)
- Dapagliflozin Impurity 15 (CAS CATO-C4X-113815)
- Dapagliflozin Impurity 152 (CAS 2459303-35-4)
- Dapagliflozin Impurity 2 (CAS 2271248-78-1)
Recommended Standards
- 2-Bromo-5-iodophenylboronic acid pinacol ester (CAS 2121512-32-9)
- 2-(3-Bromo-5-iodophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 942069-57-0)
- 1,1,1,9,9,9-Hexamethyl-3,5,7-trioctyl-3,5,7-tris((trimethylsilyl)oxy)pentasiloxane (CAS 187593-69-7)
- 1,1,1,5,5,5-Hexamethyl-3-octyl-3-((trimethylsilyl)oxy)trisiloxane (CAS 187592-85-4)
- Ibuprofen EP Impurity D (CAS 938-94-3)
- Dotinurad Impurity 72 (CAS CATO-C4X-249472)
- Cinacalcet Impurity 81 (CAS CATO-C4X-105981)
- 2,5-Dimethoxy-N-[2-(4-methylphenoxy)butyl]aniline (CAS 1040688-45-6)
- cis-4-fluorocyclohexane-1-carbaldehyde (CAS 2306250-04-2)
- Nikethamide Impurity 12 (CAS 27828-61-1)
- 2-(2-Fluoro-4-methoxy-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2820542-17-2)
- 2-(4-(Aminomethyl)-1H-1,2,3-triazol-1-yl)-N,N-diisopropylacetamide (CAS 1456370-25-4)
- Ethyl 5-amino-4,5,6,7-tetrahydro-1h-indazole-3-carboxylate (CAS 893638-27-2)
- 30003-72-6 insulin chain b oxidized (CAS 30003-72-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com