Loratadine impurity 87 CAS 130642-54-5
| CAS No. | 130642-54-5 |
| Molecular Formula | C14H11BrN2 |
| Molecular Weight | 287.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Loratadine impurity 87 (C14H11BrN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Loratadine impurity 87 (CAS 130642-54-5), a pharmacopoeial impurity reference standard (molecular formula C14H11BrN2, MW 287.15 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Loratadine impurity 87 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H11BrN2 |
| Molecular Weight | 287.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Loratadine Standards
- Loratadine Impurity 28 (CAS 3964-81-6)
- Loratadine Impurity 7 (CAS 133330-61-7)
- Loratadine Impurity 15 (CAS 133330-60-6)
- Loratadine Impurity 96 (CAS CATO-C4X-142696)
- Loratadine EP Impurity D (CAS 100643-71-8)
- Loratadine Impurity 68 (CAS 133345-21-8)
- Loratadine Impurity 76 (CAS CATO-C4X-142676)
- Loratadine Impurity 53 (CAS 107285-30-3)
Recommended Standards
- 81-86-7 6-Bromo-1H,3H-naphtho(1,8-cd)pyran-1,3-dione 1H,3H-Naphtho(1,8-cd)pyran-1,3-dione, 6-bromo- EINECS 201-382-3 (CAS 81-86-7)
- Cyclobenzaprine Impurity 3 (CAS 24167-44-0)
- 2-[4-Bromo-2-(tert-butyl)phenoxy]acetic acid 3158AE 425372-86-7 C12H15BrO3 (CAS 425372-86-7)
- Iloperidone Impurity 6 (CAS 3245-49-6)
- Papaverine EP Impurity F (CAS 139-76-4)
- Lidocaine Impurity 72 (CAS CATO-C4X-167972)
- Propiverine Impurity N1 HCl (CAS 54556-99-9)
- 2,6-Difluoro-N-pentylaniline (CAS 1040057-03-1)
- 9-[2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-9H-carbazole (CAS 1357634-60-6)
- Papuamine (CAS 112455-84-2)
- Ubidecarenone impurity 19 (CAS 5677-54-3)
- N-((9-ethyl-9H-carbazol-3-yl)methyl)-1-methoxypropan-2-amine hydrobromide (CAS 1609407-44-4)
- 2-(2-(Difluoromethoxy)-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1403988-78-2)
- [D-Glu]3-Semaglutide (CAS CATO-C4X-2226253)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com