Valsartan EP Impurity A CAS 137862-87-4
| CAS No. | 137862-87-4 |
| Molecular Formula | C24H29N5O3 |
| Molecular Weight | 435.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 435.52 g/mol gives Valsartan EP Impurity A distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Valsartan EP Impurity A (CAS 137862-87-4) is a certified pharmaceutical impurity reference standard with the molecular formula C24H29N5O3 and a molecular weight of 435.52 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Valsartan EP Impurity A is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 435.52 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Valsartan EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H29N5O3 |
| Molecular Weight | 435.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 5 |
Related Valsartan Standards
- Valsartan (CAS 137862-53-4)
- Valsartan Impurity 102 (CAS CATO-C4X-1057102)
- Valsartan Impurity 58 (CAS CATO-C4X-105758)
- Valsartan Impurity 63 (CAS CATO-C4X-105763)
- Valsartan Impurity 94 (CAS 1283097-98-2)
- Valsartan-d3 (CAS 1331908-02-1)
- Valsartan desvaleryl benzyl impurity (CAS 676129-93-4)
- (S)-(-)-Valsartan-d8 (valine-d8) (CAS 1089736-72-0)
Recommended Standards
- N-(1-Oxopentyl)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]valine (CAS 943333-68-4)
- DBCO-PEG2-amine (CAS 2250216-96-5)
- Selexipag Impurity 4 (CAS 2732400-56-3)
- 6-Chloro-N2,N4-bis(3,4-dichlorophenyl)-1,3,5-triazine-2,4(1H,3H)-diimine (CAS 30355-06-7)
- Finerenone Impurity 78 (CAS CATO-C4X-288078)
- Carbocisteine Impurity 30 (CAS CATO-C4X-201030)
- Midodrine impurity 1 (CAS CATO-C4X-30721)
- 1-Methylpyrazole-4-carbaldehyde (CAS 25016-11-9)
- 3-Benzamido-N-(2-chlorobenzyl)benzamide (CAS 708222-96-2)
- 141801-03-8 IL-1 Receptor Peptide (human) (CAS 141801-03-8)
- N-(2-(3-(1H-Imidazol-1-yl)-6-oxopyridazin-1(6H)-yl)ethyl)-2-phenylethene-1-sulfonamide (CAS 1396890-91-7)
- Itrocainide (CAS 90828-99-2)
- 3-((3-Aminopropyl)thio)propanoic acid (CAS 16496-86-9)
- HA Peptide (CAS 92000-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com