Valsartan Impurity 8 CAS 137862-78-3
| CAS No. | 137862-78-3 |
| Molecular Formula | C25H31N5O3 |
| Molecular Weight | 449.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Valsartan Impurity 8 (CAS 137862-78-3), a pharmacopoeial impurity reference standard (molecular formula C25H31N5O3, MW 449.55 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Valsartan Impurity 8 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 449.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Valsartan Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H31N5O3 |
| Molecular Weight | 449.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 5 |
Related Valsartan Standards
- Valsartan Impurity 106 (CAS CATO-C4X-1057106)
- Valsartan Impurity 112 (CAS CATO-C4X-1057112)
- Valsartan Impurity 120 (CAS 137863-48-0)
- Valsartan Impurity 125 (CAS 1894176-40-9)
- Valsartan USP Related Compound E (CAS 137863-17-3)
- Valsartan Impurity 73 (CAS CATO-C4X-105773)
- Valsartan Impurity 74 (CAS CATO-C4X-105774)
- Valsartan Impurity 75 (CAS CATO-C4X-105775)
Recommended Standards
- Valsartan Impurity 78 (CAS CATO-C4X-105778)
- Valsartan Impurity 83 (CAS CATO-C4X-105783)
- Valsartan Impurity 77 (CAS CATO-C4X-105777)
- Valsartan Impurity 93 (CAS CATO-C4X-105793)
- Cinacalcet Impurity 3 (CAS CATO-C4X-10593)
- Cariprazine Impurity 23 (CAS 1480744-25-9)
- Salbutamol EP Impurity I(HCl) (CAS CATO-C4X-117636)
- 1-(1,2-thiazol-5-yl)ethan-1-amine dihydrochloride (CAS 2044901-81-5)
- 301687-57-0 [Tetrabutylammonium] [| currency-tris(tetrachloro-1,2-benzenediolato)phosphate(V)] | currency-TRISPHAT tetrabutylammonium salt (CAS 301687-57-0)
- 1-Phenyl-2-(trifluoromethyl)quinolin-4(1H)-one (CAS 837364-35-9)
- 5-(3-Fluorophenyl)-1H-imidazol-2-amine (CAS 1517841-44-9)
- 1-(4-(1,1,2,3,3,3-Hexafluoropropoxy)phenyl)ethan-1-one (CAS 933673-41-7)
- N-(4-Aminophenyl)-2-(2-ethoxyethoxy)benzamide (CAS 1020055-73-5)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com