5-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine CAS 1378673-63-2
| CAS No. | 1378673-63-2 |
| Molecular Formula | C6H2ClF3N4 |
| Molecular Weight | 222.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine (CAS 1378673-63-2), molecular formula C6H2ClF3N4 and molecular weight 222.56 g/mol, is a CATO reference standard with documented purity and traceability.
5-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine (C6H2ClF3N4) contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H2ClF3N4 |
| Molecular Weight | 222.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 7-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrimidine (CAS 1094260-88-4)
- 7-Chloro-5-(trifluoromethyl)-1H-pyrazolo[4,3-d]pyrimidine (CAS 1211533-12-8)
- 6-Chloro-3-(trifluoromethyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1211590-25-8)
- 6-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine (CAS 1379310-87-8)
- 8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine (CAS 140911-31-5)
- 2-Chloro-6-(trifluoromethyl)-9H-purine (CAS 1998-64-7)
- 5-Chloro-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-c]pyrimidine (CAS 877402-89-6)
- 5-chloro-7-(trifluoromethyl)-1H-pyrazolo[4,3-d]pyrimidine (CAS 2821754-61-2)
Recommended Standards
- 2-Amino-4-chloro-6-(trifluoromethyl)pyrimidine-5-carbonitrile (CAS 951753-89-2)
- 3-Chloro-2-cyano-5-(trifluoromethyl)pyridine 1-Oxide (CAS 1823184-13-9)
- 6-Chloro-2-(trifluoromethyl)oxazolo[5,4-b]pyridine (CAS 1196153-60-2)
- Methyl 4-chloro-2,2,3,3-tetrafluoro-4-oxobutanoate (CAS 21543-97-5)
- 2'-Hydroxy-5'-methyl-3'-nitroacetophenone 1-(2-hydroxy-5-methyl-3-nitrophenyl)ethanone 2-hydroxy-5-methyl-3-nitroacetophenone 2'-hydroxy-3'-nitro-5'-methylacetophenone 66108-30-3 (CAS 66108-30-3)
- 5-(Tert-butyl) 2-methyl 6,7-dihydrooxazolo[5,4-c]pyridine-2,5(4H)-dicarboxylate (CAS 259809-74-0)
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