8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine CAS 140911-31-5
| CAS No. | 140911-31-5 |
| Molecular Formula | C6H2ClF3N4 |
| Molecular Weight | 222.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine (CAS 140911-31-5), a certified reference material (molecular formula C6H2ClF3N4, MW 222.56 g/mol) for analytical method development and quality control.
Owing to a nitrile group, fluorine/chlorine substitution, an aromatic ring system, 8-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 222.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H2ClF3N4 |
| Molecular Weight | 222.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 7-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrimidine (CAS 1094260-88-4)
- 7-Chloro-5-(trifluoromethyl)-1H-pyrazolo[4,3-d]pyrimidine (CAS 1211533-12-8)
- 6-Chloro-3-(trifluoromethyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1211590-25-8)
- 5-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine (CAS 1378673-63-2)
- 6-Chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine (CAS 1379310-87-8)
- 2-Chloro-6-(trifluoromethyl)-9H-purine (CAS 1998-64-7)
- 5-Chloro-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-c]pyrimidine (CAS 877402-89-6)
- 5-chloro-7-(trifluoromethyl)-1H-pyrazolo[4,3-d]pyrimidine (CAS 2821754-61-2)
Recommended Standards
- 2-Amino-4-chloro-6-(trifluoromethyl)pyrimidine-5-carbonitrile (CAS 951753-89-2)
- 6-Chloro-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-b]pyridazine (CAS 882856-60-2)
- 3-Chloro-2-cyano-5-(trifluoromethyl)pyridine 1-Oxide (CAS 1823184-13-9)
- 6-Chloro-2-(trifluoromethyl)-9H-purine (CAS 1998-63-6)
- [3-Fluoro-4-(oxetan-3-yloxy)phenyl]methanamine (CAS 1349709-03-0)
- (2e)-3-(5-Bromofuran-2-yl)-2-cyanoprop-2-enethioamide (CAS 299934-47-7)
- tert-Butyl 5-bromo-2-hydroxy-1H-indole-1-carboxylate (CAS 1881321-13-6)
- Benzyl 2-methyl-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate (CAS 1440526-52-2)
- Methyl 1H,2H,3H,4H-pyrrolo[1,2-a]pyrazine-8-carboxylate (CAS 1499207-49-6)
- (R)-2-(2,4-dichlorophenyl)pyrrolidine (CAS 1213358-39-4)
- 4-(5-((3,4-Dihydroisoquinolin-2(1H)-yl)methyl)-1H-tetrazol-1-yl)butanoic acid hydrochloride (CAS 1443279-55-7)
- 1-(Difluoromethyl)-4-(trifluoromethoxy)benzene (CAS 934738-22-4)
- Methyl 3-cyano-5-hydroxy-2-methoxybenzoate (CAS 1807291-49-1)
- Tau Peptide (337-368) (Repeat 4 Domain) trifluoroacetate salt (CAS 330456-27-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com