Oxazepam impurity 12 CAS 13788-59-5
| CAS No. | 13788-59-5 |
| Molecular Formula | C15H12ClNO2 |
| Molecular Weight | 273.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Oxazepam impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Oxazepam impurity 12 (CAS 13788-59-5, C15H12ClNO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Oxazepam impurity 12 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 273.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C15H12ClNO2 |
| Molecular Weight | 273.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Oxazepam Standards
Recommended Standards
- Epinastine Impurity 17 (CAS 23207-75-2)
- Carprofen (CAS 53716-49-7)
- Pranoprofen Impurity 22 (CAS 146330-68-9)
- 6-Chloro-1-methyl-N-(2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 100376-17-8)
- Baricitinib Impurity N16 (CAS 2402776-80-9)
- Regadenoson Impurity 49 (CAS 120595-74-6)
- Avibactam Impurity 47 (CAS CATO-C4X-134847)
- 5,5-Dimethylpiperidin-3-ol (CAS 806596-58-7)
- 2-(3,4,5-Trifluorophenyl)ethane-1-thiol (CAS 1314904-43-2)
- 3-(Cyclopropylmethoxy)pyridine (CAS 1243279-25-5)
- (5-((3,5-Dichlorophenyl)thio)-1-ethyl-4-isopropyl-1H-imidazol-2-yl)methanol (CAS 178979-14-1)
- N-Didesmethyl Loperamide (CAS 66164-06-5)
- methyl 2-amino-2-{pyrrolo[2,1-f][1,2,4]triazin-7-yl}acetate (CAS 2089698-95-1)
- Pancreatic Polypeptide (1-17)-(Ala31,Aib32)-Neuropeptide Y (18-36) (human) trifluoroacetate salt (CAS 313988-70-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com