3,4-Difluoro-5-hydroxyphenylboronic acid CAS 1379466-84-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1379466-84-8
Molecular FormulaC6H5BF2O3
Molecular Weight173.91 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3,4-Difluoro-5-hydroxyphenylboronic acid CAS 1379466-84-8 chemical structure

Description

The occurrence of 3,4-Difluoro-5-hydroxyphenylboronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3,4-Difluoro-5-hydroxyphenylboronic acid (CAS 1379466-84-8) is a high-purity analytical reference standard with the molecular formula C6H5BF2O3 and a molecular weight of 173.91 g/mol.

3,4-Difluoro-5-hydroxyphenylboronic acid (C6H5BF2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3,4-Difluoro-5-hydroxyphenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H5BF2O3
Molecular Weight173.91 g/mol
Purity97%+
StorageStore at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1991
Halogen ContentF-containing

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