4,5-Difluoro-2-hydroxyphenylboronic acid CAS 1432610-22-4
| CAS No. | 1432610-22-4 |
| Molecular Formula | C6H5BF2O3 |
| Molecular Weight | 173.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4,5-Difluoro-2-hydroxyphenylboronic acid (CAS 1432610-22-4), a certified reference material (molecular formula C6H5BF2O3, MW 173.91 g/mol) for analytical method development and quality control.
Structurally, 4,5-Difluoro-2-hydroxyphenylboronic acid (C6H5BF2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.5, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 173.91 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5BF2O3 |
| Molecular Weight | 173.91 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Difluoro Standards
- (3,5-Difluoro-4-hydroxyphenyl)boronic acid (CAS 1132666-81-9)
- (3,5-Difluoro-2-hydroxyphenyl)boronic acid (CAS 1150114-51-4)
- (2,5-Difluoro-4-hydroxyphenyl)boronic acid (CAS 1229584-22-8)
- (2,3-Difluoro-6-hydroxyphenyl)boronic acid (CAS 1238196-62-7)
- 3,4-Difluoro-5-hydroxyphenylboronic acid (CAS 1379466-84-8)
- (2,4-Difluoro-6-hydroxyphenyl)boronic acid (CAS 1973391-08-0)
- (2,5-Difluoro-3-hydroxyphenyl)boronic acid (CAS 919355-35-4)
- (3,6-Difluoro-2-hydroxyphenyl)boronic acid (CAS 2246616-05-5)
Recommended Standards
- 2,4-Difluoro-5-hydroxyphenylboronic acid (CAS 2096330-91-3)
- 2,6-Difluoro-3-hydroxyphenylboronic Acid (CAS 957065-86-0)
- Dibromomethane (CAS 74-95-3)
- 3,4-Difluoro-2-hydroxyphenylboronic acid (CAS 2059147-53-2)
- 2-Hexanoylcyclohexan-1-one (CAS 22122-93-6)
- 6-Amino-2,4-dimethyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 70488-69-6)
- 5-Bromo-N-cyclopropylfuran-2-carboxamide (CAS 352682-00-9)
- 3-{[1,2,4]triazolo[4,3-a]pyridin-3-yl}propanoic acid (CAS 933742-81-5)
- Zinc titanium oxide, 99.9% (metals basis) (CAS 12036-69-0)
- 6-Iodo-2-phenylimidazo[1,2-a]pyridine (CAS 61982-63-6)
- tert-Butyl (5-bromo-4-(trifluoromethyl)pyridin-2-yl)carbamate (CAS 1542268-23-4)
- Fmoc-(s)-3-amino-2-(phenylsulfonylamino)-propionic acid (CAS 273399-94-3)
- 2-Hydroxy-1-methylpyrrolidine (CAS 7225-08-3)
- D-Thr5-Tirzepatide (CAS CATO-CPTD788926)
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