(2,5-Difluoro-3-hydroxyphenyl)boronic acid CAS 919355-35-4

Description

The occurrence of (2,5-Difluoro-3-hydroxyphenyl)boronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(2,5-Difluoro-3-hydroxyphenyl)boronic acid (CAS 919355-35-4), molecular formula C6H5BF2O3 and molecular weight 173.91 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (2,5-Difluoro-3-hydroxyphenyl)boronic acid (C6H5BF2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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