4-(Cyclobutylmethoxy)-3,5-difluorobenzoic acid CAS 1380300-36-6
| CAS No. | 1380300-36-6 |
| Molecular Formula | C12H12F2O3 |
| Molecular Weight | 242.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(Cyclobutylmethoxy)-3,5-difluorobenzoic acid (CAS 1380300-36-6) is a high-purity analytical reference standard with the molecular formula C12H12F2O3 and a molecular weight of 242.22 g/mol.
Structurally, 4-(Cyclobutylmethoxy)-3,5-difluorobenzoic acid (C12H12F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 242.22 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12F2O3 |
| Molecular Weight | 242.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Cyclobutylmethoxy Standards
- 3-(Cyclobutylmethoxy)-1-methyl-1H-indazole-6-carbaldehyde (CAS 1923064-98-5)
- 2-(Cyclobutylmethoxy)-3-methoxybenzoic acid (CAS 339539-38-7)
- 6-(Cyclobutylmethoxy)-2-methylpyrimidine-4-carboxylic acid (CAS 1707563-23-2)
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- 2-(Cyclobutylmethoxy)-4,6-dimethylbenzaldehyde (CAS 1708037-52-8)
- 6-Cyclobutylmethoxy-indan-1-one (CAS 1383985-15-6)
- 4-(Cyclobutylmethoxy)-3,5-difluoroaniline (CAS 1707369-83-2)
- 2-(cyclobutylmethoxy)ethane-1-sulfonyl chloride (CAS 1909318-83-7)
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- BI-87G3 (CAS 2207-44-5)
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- 1-(3-Bromophenyl)-5-hydroxy-2-(hydroxymethyl)pyridin-4(1H)-one (CAS 1333331-97-7)
- 3-(Chloromethyl)-n,n-dimethyl-1,2,4-thiadiazol-5-amine (CAS 32577-97-2)
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- Ac-(5-31)Semaglutide (CAS CATO-C4X-2226279)
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