Finerenone Impurity 215 CAS 1381846-22-5
| CAS No. | 1381846-22-5 |
| Molecular Formula | C8H4Br3N |
| Molecular Weight | 353.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 353.84 g/mol gives Finerenone Impurity 215 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Finerenone Impurity 215 (CAS 1381846-22-5, C8H4Br3N) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Finerenone Impurity 215 (C8H4Br3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4Br3N |
| Molecular Weight | 353.84 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Finerenone Standards
- Finerenone Impurity 137 (CAS CATO-C4X-2880137)
- Finerenone Impurity 78 (CAS CATO-C4X-288078)
- Finerenone Impurity 241 (CAS 3046141-71-0)
- Finerenone Impurity 54 (CAS CATO-C4X-288054)
- Finerenone Impurity 58 (CAS CATO-C4X-288058)
- Finerenone Impurity 268 (CAS CATO-C4X-2880268)
- Finerenone Impurity 36 (CAS 2087452-81-9)
- Finerenone Impurity 103 (CAS CATO-C4X-2880103)
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