Apremilast impurity 16 CAS 1384439-80-8
| CAS No. | 1384439-80-8 |
| Molecular Formula | C17H16N2O6S |
| Molecular Weight | 376.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Apremilast impurity 16 is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Apremilast impurity 16 (CAS 1384439-80-8) is a certified pharmaceutical impurity reference standard with the molecular formula C17H16N2O6S and a molecular weight of 376.38 g/mol.
Apremilast impurity 16 (C17H16N2O6S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Apremilast impurity 16 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H16N2O6S |
| Molecular Weight | 376.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Apremilast Standards
- Apremilast Impurity 84 (CAS 22895-28-9)
- Apremilast Impurity 49 (CAS CATO-C4X-100949)
- Apremilast Impurity 99 (CAS CATO-C4X-100999)
- Apremilast Impurity 39 (CAS CATO-C4X-100939)
- Apremilast Impurity 88 (CAS CATO-C4X-100988)
- Apremilast Impurity 85 (CAS 88687-92-7)
- Apremilast impurity 93 (CAS 2733027-41-1)
- Apremilast Impurity 35 (CAS 253168-83-1)
Recommended Standards
- N-(3,4-Difluorophenyl)-2-((4-ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 573972-53-9)
- Trelagliptin Impurity 29 (CAS 1917324-15-2)
- N-(2,4-Difluorophenyl)-2-(3,4-dimethoxyphenyl)-1,3-thiazole-4-carboxamide (CAS 400080-55-9)
- Cefamandole Nafate EP Impurity A (CAS CATO-C4X-122131)
- Verapamil Impurity 17 (CAS CATO-C4X-177817)
- Imidapril Impurity N1 (CAS 120294-09-9)
- Palbociclib Impurity 159 (CAS 2204368-66-9)
- (4-Nitro-3-(trifluoromethyl)phenyl)methanol (CAS 936234-83-2)
- Methyl 2-amino-2-cyclopropylacetate (CAS 768356-83-8)
- N,N-dimethyl-2-phenylhydrazine-1-sulfonamide (CAS 1239755-42-0)
- 2-((4-Isopropylphenyl)thio)-1-methyl-5-nitro-1H-indole-3-carbaldehyde (CAS 338416-13-0)
- Pentamidine Diamidoxime (CAS 101689-95-6)
- 4667-99-6 Chlorotriethoxysilane Silane, chlorotriethoxy- EINECS 225-112-9 Triethoxychlorosilane (CAS 4667-99-6)
- Neuropeptide Y (3-36) (human, rat) trifluoroacetate salt (CAS 150138-78-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com