Palbociclib Impurity 159 CAS 2204368-66-9
| CAS No. | 2204368-66-9 |
| Molecular Formula | C24H29N7O2 |
| Molecular Weight | 447.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Palbociclib Impurity 159 (CAS 2204368-66-9), a pharmacopoeial impurity reference standard (molecular formula C24H29N7O2, MW 447.53 g/mol) used for the identification and quantification of trace impurities in APIs.
Palbociclib Impurity 159 (C24H29N7O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Palbociclib Impurity 159 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H29N7O2 |
| Molecular Weight | 447.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 7 |
Related Palbociclib Standards
- Palbociclib Impurity N87 (CAS 2205035-04-5)
- Palbociclib (CAS 571190-30-2)
- Palbociclib Impurity 11 (CAS CATO-C4X-112511)
- Palbociclib Impurity 157 (CAS CATO-C4X-1125157)
- Palbociclib Impurity 41 (CAS CATO-C4X-112541)
- Palbociclib Impurity 7 (CAS CATO-C3D-1456)
- Palbociclib Impurity 20 (CAS CATO-C3D-1542)
- Palbociclib Impurity 22 (CAS 1376615-91-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com