Apremilast Impurity 84 CAS 22895-28-9
| CAS No. | 22895-28-9 |
| Molecular Formula | C16H10N2O9 |
| Molecular Weight | 374.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 374.26 g/mol gives Apremilast Impurity 84 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Apremilast Impurity 84 (CAS 22895-28-9), a pharmacopoeial impurity reference standard (molecular formula C16H10N2O9, MW 374.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Apremilast Impurity 84 (C16H10N2O9) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Apremilast Impurity 84 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H10N2O9 |
| Molecular Weight | 374.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 2 |
Related Apremilast Standards
- Apremilast impurity 16 (CAS 1384439-80-8)
- Apremilast Impurity 49 (CAS CATO-C4X-100949)
- Apremilast Impurity 99 (CAS CATO-C4X-100999)
- Apremilast Impurity 88 (CAS CATO-C4X-100988)
- Apremilast Impurity 85 (CAS 88687-92-7)
- Apremilast Impurity 39 (CAS CATO-C4X-100939)
- Apremilast impurity 93 (CAS 2733027-41-1)
- Apremilast Impurity 35 (CAS 253168-83-1)
Recommended Standards
- 1-benzyl-3-[(2,6-dichlorophenyl)methoxy]-2-methyl-1,4-dihydropyridin-4-one 338965-18-7 6K-023 (CAS 338965-18-7)
- Belumosudil Impurity 45 (CAS CATO-C4X-298845)
- 5-Iodo-2-isopropoxy-4-(1-methylpiperidin-4-yl)aniline (CAS 2306275-75-0)
- 1024771-81-0 Aza(3-(4-bromophenyl)-7-propyl(6,7,8-trihydrocinnolin-5-ylidene))methoxymethane MFCD00170706 (CAS 1024771-81-0)
- Bicalutamide EP Impurity L (CAS 2711603-77-7)
- Brexpiprazole Impurity 10 (CAS 1191900-58-9)
- Ruxolitinib Impurity 41 (CAS CATO-C4X-205841)
- Ethyl 7-oxo-7-(m-tolyl)heptanoate (CAS 898751-54-7)
- 2-Methyl-2-(3-nitrophenyl)-1,3-dioxolane (CAS 51226-13-2)
- Ethyl 2-(6-Fluoro-3-indolyl)-2-oxoacetate (CAS 213886-56-7)
- 5-(Piperidin-4-yl)-3-(2,4,6-trifluorophenyl)-1,2,4-oxadiazole (CAS 1539884-65-5)
- Di-[3-((R)-2,2'-dihydroxy-1,1'-binaphthylmethyl)]ether, lanthanum(III) salt, tetrahydrofuran adduct (CAS 321837-08-5)
- 1-(1-Ethyl-5-fluoro-1H-pyrazol-4-yl)-N-((1-methyl-1H-pyrazol-3-yl)methyl)methanamine hydrochloride (CAS 1856093-76-9)
- Semaglutide impurity 29 (CAS 110990-08-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com