Apremilast impurity 63 CAS 1384967-20-7
| CAS No. | 1384967-20-7 |
| Molecular Formula | C20H20N2O7S |
| Molecular Weight | 432.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Apremilast impurity 63.
As a process- or degradation-related impurity, Apremilast impurity 63 (CAS 1384967-20-7, C20H20N2O7S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Apremilast impurity 63 (C20H20N2O7S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Apremilast impurity 63 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H20N2O7S |
| Molecular Weight | 432.45 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Apremilast Standards
- Apremilast impurity 17 (CAS CATO-C4X-100917)
- Apremilast Impurity 26 (CAS CATO-C4X-100926)
- Apremilast Impurity 100 (CAS CATO-C4X-1009100)
- Apremilast Impurity 117 (CAS CATO-C4X-1009117)
- Apremilast Impurity 37 (CAS 1407140-51-5)
- Apremilast impurity 13 (CAS CATO-C4X-100913)
- Apremilast impurity 89 (CAS CATO-C4X-100989)
- Apremilast impurity 90 (CAS CATO-C4X-100990)
Recommended Standards
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- Riociguat Impurity 17 (CAS CATO-C4X-174917)
- 2-((9,10-Dioxo-9,10-dihydroanthracen-2-yl)amino)-2-oxoethyl 2-(methylthio)nicotinate (CAS 479522-97-9)
- Dopamine Impurity 96 (CAS CATO-C4X-190896)
- Riociguat Impurity N20 (CAS 256499-19-1)
- Cefazolin Impurity 75 (CAS CATO-C4X-157775)
- N-(sec-Butyl)-6-chloro-2-pyrazinamine (CAS 1220027-83-7)
- N-(4-Methylpyridin-2-yl)-6-(piperazin-1-yl)pyridazin-3-amine (CAS 1706446-74-3)
- Methyl 2-phenylpyrimidine-5-carboxylate (CAS 64074-29-9)
- Ethyl 2-phenylimidazo[1,2-a]pyridine-3-carboxylate (CAS 119448-82-7)
- 2-{[4-(4-chloro-2-fluorobenzenesulfonamido)phenyl]formamido}acetic acid (CAS 847751-79-5)
- Methyl 2-{3-[4-(ethylcarbamoyl)-3-fluorophenyl]phenyl}acetate (CAS 1820603-49-3)
- Influenza PR8 Hemagglutinin Peptide (110-119) (H-6312.0005) (CAS 132031-50-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com