Apremilast impurity 89 CAS CATO-C4X-100989
| CAS No. | CATO-C4X-100989 |
| Molecular Formula | C20H24N2O7S |
| Molecular Weight | 436.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Apremilast impurity 89 (CAS CATO-C4X-100989), a pharmacopoeial impurity reference standard (molecular formula C20H24N2O7S, MW 436.48 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Apremilast impurity 89 (C20H24N2O7S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Apremilast impurity 89 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H24N2O7S |
| Molecular Weight | 436.48 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Apremilast Standards
- Apremilast impurity 13 (CAS CATO-C4X-100913)
- Apremilast impurity 90 (CAS CATO-C4X-100990)
- Apremilast Impurity 100 (CAS CATO-C4X-1009100)
- Apremilast impurity 17 (CAS CATO-C4X-100917)
- Apremilast impurity 63 (CAS 1384967-20-7)
- Apremilast Impurity 26 (CAS CATO-C4X-100926)
- Apremilast Impurity 117 (CAS CATO-C4X-1009117)
- Apremilast Impurity 37 (CAS 1407140-51-5)
Recommended Standards
- MLS000389544 (CAS 573965-48-7)
- Linezolid Impurity 93 (CAS CATO-C4X-107393)
- Methyl 4-6-O-benzylidene-2-3-di-O-p-toluenesulfonyl-α-D-glucopyranoside (CAS 70774-92-4)
- Olaparib Impurity 116 (CAS CATO-C4X-1135116)
- Sugammadex Impurity 52 (CAS 2458187-21-6)
- Rimegepant Impurity 52 DiHCl (CAS CATO-C4X-248752)
- Isavuconazole Impurity 49 (CAS CATO-C4X-123649)
- 5'-(Trifluoromethyl)-1',2'-dihydrospiro[cyclopropane-1,3'-indole]-2'-one (CAS 1360898-86-7)
- 1-(Difluoromethyl)-3-fluoro-2-iodobenzene (CAS 1261647-51-1)
- 3'-Amino-[1,1'-biphenyl]-4-carboxylicacid (CAS 124221-69-8)
- 2-Methyl-1-(3-methyl-1,2,4-oxadiazol-5-yl)propan-1-amine hydrochloride (CAS 1311316-14-9)
- Loxoprofen Impurity 160 (CAS CATO-C4X-1488160)
- 4-(2-Methoxypyrimidin-5-yl)benzaldehyde (CAS 1785548-22-2)
- Endo-Gly4-Semaglutide (CAS CATO-C4X-222679)
Why CATO?
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