Riociguat Impurity N20 CAS 256499-19-1
| CAS No. | 256499-19-1 |
| Molecular Formula | C14H12FN5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, Riociguat Impurity N20 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 305.74 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Riociguat Impurity N20 (CAS 256499-19-1) is a certified pharmaceutical impurity reference standard with the molecular formula C14H12FN5HCl and a molecular weight of 305.74 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Riociguat Impurity N20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H12FN5 HCl |
| Molecular Weight | 305.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Riociguat Standards
- Riociguat-13C-d3 (CAS 1304478-43-0)
- Riociguat Impurity 2 (CAS 1361569-10-9)
- Riociguat Impurity 16 (CAS 1361569-18-7)
- Riociguat Impurity 18 (CAS 1361569-23-4)
- Riociguat Impurity 1 (CAS 1702271-98-4)
- Riociguat Impurity N10 (CAS 2101651-50-5)
- Riociguat Impurity N3 (CAS 2512205-25-1)
- Riociguat Impurity 30 (CAS 2518331-19-4)
Recommended Standards
- Halobetasol Impurity 3 (CAS 181527-42-4)
- Voglibose Impurity 9 (CAS CATO-C4X-17809)
- Gadoteridol Impurity 53 (CAS CATO-C4X-225753)
- 3,6-Dichloro-2-(difluoromethoxy)benzaldehyde (CAS 1803830-86-5)
- 4-formyl-1H-imidazole-5-carboxylic acid (CAS 1321600-00-3)
- Methyl 4-sulfamoylthiophene-3-carboxylate (CAS 59337-78-9)
- 2-(pyrrolidin-2-yl)-4,5,6,7-tetrahydro-1H-1,3-benzodiazole dihydrochloride (CAS 1417634-98-0)
- Dichlorobis(bipyridine)ruthenium (CAS 15746-57-3)
- (E)-3-Methyl-5-(2-methylbut-1-en-1-yl)isoxazole (CAS 344881-41-0)
- Tau Peptide (274-288) trifluoroacetate salt (CAS 330456-39-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com