Agomelatine Impurity 1 CAS 1385018-58-5
| CAS No. | 1385018-58-5 |
| Molecular Formula | C28H29NO3 |
| Molecular Weight | 427.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Agomelatine Impurity 1 (CAS 1385018-58-5) is a certified pharmaceutical impurity reference standard with the molecular formula C28H29NO3 and a molecular weight of 427.53 g/mol.
Agomelatine Impurity 1 (C28H29NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Agomelatine Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H29NO3 |
| Molecular Weight | 427.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related Agomelatine Standards
- Agomelatine Impurity 2 (CAS 185421-27-6)
- Agomelatine impurity 31 (CAS CATO-C4X-110831)
- Agomelatine Impurity 4 (CAS CATO-C4X-11084)
- Agomelatine Impurity 9 (CAS CATO-C4X-11089)
- Agomelatine Impurity 3 (CAS 1385018-57-4)
- Agomelatine Diacetyl Impurity (CAS 1379005-34-1)
- Agomelatine Impurity 53 (CAS CATO-C4X-110853)
- Agomelatine Impurity 28 (CAS CATO-C4X-110828)
Recommended Standards
- 239466-40-1 ACE056 Acetic acid, 2-[4-hydroxy-1-(triphenylmethyl)-3-piperidinylidene]-, ethyl ester, (2E)- (CAS 239466-40-1)
- (R)-Ranolazine (CAS 114246-80-9)
- m-PEG9-Amine (CAS 211859-73-3)
- Mozavaptan (CAS 137975-06-5)
- Ticagrelor impurity 95 (CAS CATO-C4X-109395)
- Vortioxetine Impurity 101 (CAS 107832-66-6)
- Relebactam Impurity 13 (CAS CATO-C4X-214413)
- Diphenylphosphinic acid ethyl ester (CAS 1733-55-7)
- 1-Difluoromethanesulfonyl-4-fluorobenzene (CAS 153698-38-5)
- 5,5-Dimethyl-3-propionyloxazolidin-2-one (CAS 223906-48-7)
- 5-(4-Bromophenyl)-4-(3-fluoro-4-methylbenzoyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618073-90-8)
- 1,3-Diphenyl imidodicarbonate (CAS 99911-94-1)
- 6-Bromo-N-methyl-2-pyrazinamine (CAS 1823878-78-9)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com