Roflumilast USP Related Compound B CAS 1391052-76-8
| CAS No. | 1391052-76-8 |
| Molecular Formula | C13H8Cl2F2N2O3 |
| Molecular Weight | 349.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Roflumilast USP Related Compound B is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 349.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Roflumilast USP Related Compound B (CAS 1391052-76-8), a certified reference material (molecular formula C13H8Cl2F2N2O3, MW 349.12 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Roflumilast USP Related Compound B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H8Cl2F2N2O3 |
| Molecular Weight | 349.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Roflumilast Standards
- Roflumilast Impurity 36 (CAS CATO-C4X-108436)
- Roflumilast USP Related Compound A (CAS 475271-62-6)
- Roflumilast Impurity 60 (CAS CATO-C4X-193560)
- Roflumilast Impurity 61 (CAS CATO-C4X-193561)
- Roflumilast Impurity 57 (CAS CATO-C4X-108457)
- Roflumilast Impurity 38 (CAS CATO-C4X-108438)
- Roflumilast Impurity 42 (CAS CATO-C4X-108442)
- Roflumilast impurity 20 (CAS 2206113-97-3)
Recommended Standards
- Tert-butyl 2-iodo-5-nitrobenzoate (CAS 250684-62-9)
- Florpyrauxifen (CAS 943832-81-3)
- Methyl 4-acetamido-5-iodo-2-methoxybenzoate (CAS 201214-53-1)
- Methyl 3-(3,4-dichlorophenyl)-5-(trifluoromethyl)benzoate (CAS 1820640-30-9)
- 6-(Chloromethyl)-5-(difluoromethyl)-3-methylpyridin-2-amine (CAS 1806816-55-6)
- [methyl(propyl)sulfamoyl]amine (CAS 1094790-34-7)
- 5-Ethyl-1-isopropyl-1h-pyrazole (CAS 1007489-53-3)
- [3-(4-Nitrophenyl)aziridin-2-yl]methanol (CAS 1858242-57-5)
- 2-(3-Fluorobenzoyl)-1-methyl-1h-imidazole (CAS 1247473-86-4)
- Methyl 2-(3-chlorobenzamido)-5-((4-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 505096-64-0)
- FGIN-1-27, 98% (CAS 142720-24-9)
- (R)-2,3-dihydro-1H-indene-1-carboxylic acid (CAS 877-01-0)
- 2-(3-Chlorophenyl)-7-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile (CAS 860610-99-7)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com