Roflumilast Impurity 42 CAS CATO-C4X-108442
| CAS No. | CATO-C4X-108442 |
| Molecular Formula | C14H16F2O5S |
| Molecular Weight | 334.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Roflumilast Impurity 42 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Roflumilast Impurity 42 (CAS CATO-C4X-108442) is a certified pharmaceutical impurity reference standard with the molecular formula C14H16F2O5S and a molecular weight of 334.34 g/mol.
Roflumilast Impurity 42 (C14H16F2O5S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H16F2O5S |
| Molecular Weight | 334.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Roflumilast Standards
- Roflumilast impurity 20 (CAS 2206113-97-3)
- Roflumilast Impurity 38 (CAS CATO-C4X-108438)
- Roflumilast Impurity 60 (CAS CATO-C4X-193560)
- Roflumilast Impurity 61 (CAS CATO-C4X-193561)
- Roflumilast USP Related Compound B (CAS 1391052-76-8)
- Roflumilast Impurity 36 (CAS CATO-C4X-108436)
- Roflumilast USP Related Compound A (CAS 475271-62-6)
- Roflumilast Impurity 57 (CAS CATO-C4X-108457)
Recommended Standards
- N-(6-ethoxybenzo[d]thiazol-2-yl)-2,6-difluorobenzamide (CAS 476277-40-4)
- N-(2-((3-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)oxy)ethyl)pyridine-3-sulfonamide (CAS 1021263-31-9)
- N-(4-(pyrrolidin-1-yl)phenyl)-3-(trifluoromethyl)benzamide (CAS 251097-28-6)
- Ethyl 4-((1-(3-fluorophenyl)-1H-tetrazol-5-yl)methyl)piperazine-1-carboxylate (CAS 1049407-95-5)
- Moxifloxacin Impurity 100 (CAS CATO-C4X-1074100)
- Istradefylline Impurity 22 (CAS 1453190-01-6)
- Cyclophosphamide Impurity 46 (CAS CATO-C4X-230646)
- 4-(Chloromethyl)-4-isobutyltetrahydro-2h-pyran (CAS 1478427-55-2)
- 2-[2-(2-Chlorophenyl)-4-phenyl-1,3-thiazol-5-yl]-N-phenylacetamide (CAS 338957-25-8)
- (e,e)-2,4-Heptadien-1-ol (CAS 33467-79-7)
- 2-[2-(3-aminophenyl)-1H-imidazol-1-yl]acetic acid (CAS 1247935-00-7)
- 1,1'-((6-Phenyl-1,3,5-triazine-2,4-diyl)bis(azanediyl))bis(anthracene-9,10-dione) (CAS 4118-16-5)
- Ethyl 2-(2-chloropropanamido)-5-phenylthiophene-3-carboxylate (CAS 565165-67-5)
- D-Phe22-Tirzepatide (CAS CATO-CPTD788912)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com