Roflumilast Impurity 61 CAS CATO-C4X-193561
| CAS No. | CATO-C4X-193561 |
| Molecular Formula | C13H17BrCl2O |
| Molecular Weight | 340.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Roflumilast Impurity 61 is closely related to a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Roflumilast Impurity 61 (CAS CATO-C4X-193561) is a certified pharmaceutical impurity reference standard with the molecular formula C13H17BrCl2O and a molecular weight of 340.08 g/mol.
Structurally, Roflumilast Impurity 61 (C13H17BrCl2O) contains a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 340.08 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Roflumilast Impurity 61 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H17BrCl2O |
| Molecular Weight | 340.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
Related Roflumilast Standards
- Roflumilast Impurity 60 (CAS CATO-C4X-193560)
- Roflumilast Impurity 38 (CAS CATO-C4X-108438)
- Roflumilast Impurity 42 (CAS CATO-C4X-108442)
- Roflumilast impurity 20 (CAS 2206113-97-3)
- Roflumilast USP Related Compound B (CAS 1391052-76-8)
- Roflumilast Impurity 36 (CAS CATO-C4X-108436)
- Roflumilast USP Related Compound A (CAS 475271-62-6)
- Roflumilast Impurity 57 (CAS CATO-C4X-108457)
Recommended Standards
- Diethyl (4-iodophenyl)phosphonate (CAS 103697-17-2)
- 2-Iodo-1-(2,2,2-trifluoroethyl)-1H-indol-4-amine (CAS 2127096-38-0)
- 3-(2-Bromophenyl)-3-(2,2,2-trifluoroacetamido)propanoic acid (CAS 117291-11-9)
- 2-[3,5-Bis(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 69807-91-6)
- Eldecalcitol Impurity 41 (CAS 214351-92-5)
- Labetalol Impurity 21 (CAS 33254-88-5)
- CAS 30718-13-9 (CAS 30718-13-9)
- N-(1,2-Dimethylheptyl)-N-(diphenylphosphino)-P,P-diphenylphosphinous amide (CAS 1239919-49-3)
- (3-Fluoro-5-((2-methoxyphenyl)carbamoyl)phenyl)boronic acid (CAS 2096335-66-7)
- N-(2-methyl-4,6-dioxo-1,4,5,6-tetrahydropyrimidin-5-yl)acetamide (CAS 954226-09-6)
- 4-Aminobicyclo[2.2.2]octane-1-carbonitrile hydrochloride (CAS 160133-27-7)
- methyl 8-bromo-3-iodo-naphthalene-1-carboxylate (CAS 2387598-99-2)
- Regadenoson Impurity 11 (CAS 24723-77-1)
- [His]1+12-Semaglutide (CAS CATO-C4X-2226178)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com