Haloperidol EP Impurity C CAS 1391052-87-1
| CAS No. | 1391052-87-1 |
| Molecular Formula | C23H27ClFNO2 |
| Molecular Weight | 403.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 403.92 g/mol gives Haloperidol EP Impurity C distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Haloperidol EP Impurity C (CAS 1391052-87-1) is a certified pharmaceutical impurity reference standard with the molecular formula C23H27ClFNO2 and a molecular weight of 403.92 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Haloperidol EP Impurity C is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 403.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H27ClFNO2 |
| Molecular Weight | 403.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Haloperidol Standards
- trans-Haloperidol N-Oxide (CAS 150214-93-0)
- Haloperidol impurity 25 (CAS 150214-94-1)
- Haloperidol Impurity 9 (CAS 148406-51-3)
- Haloperidol-d4 (CAS 1189986-59-1)
- Haloperidol Impurity 15 (CAS CATO-C4X-146115)
- Haloperidol EP Impurity B (CAS 1391052-53-1)
- Haloperidol (CAS 52-86-8)
- Haloperidol Impurity 11 (CAS 75478-79-4)
Recommended Standards
- [N,N'-Bis(2-hydroxy-6-methoxybenzylidene)propane-1,3-diamine]copper(II) (CAS 1035198-26-5)
- (1E)-N-(4-Chlorophenyl)-1-{5-[(4-methylphenyl)sulfanyl]-2-phenyl-1H-imidazol-4-yl}methanimine (CAS 303986-87-0)
- 1-(2-Chlorophenyl)-4-{7-methyl-2-phenylimidazo[1,2-a]pyrimidin-5-yl}piperazine (CAS 439096-71-6)
- 3-(2-Chlorobenzyl)-2-(isopropylthio)-6,7-dimethoxyquinazolin-4(3H)-imine (CAS 860610-73-7)
- Cephalexin Impurity 13 (CAS 1323247-65-9)
- Ceftizoxime Open-ring decarboxylation Dimer Impurity 56 (CAS CATO-C4X-179356)
- Iohexol impurity 43 (CAS CATO-C4X-166443)
- 2,2-Dimethyl-4-(thiophen-3-yl)butan-1-ol (CAS 1479062-18-4)
- 4-Chloro-1H-imidazole (CAS 15965-31-8)
- Quinoxidine (Chinoxidin) (CAS 10103-89-6)
- 5-Mercapto-[1,2,4]triazolo[4,3-a]pyrimidin-7(1H)-one (CAS 161715-52-2)
- 4,4'-Bis(dibenzazepin-1-yl)biphenyl (CAS 204200-08-8)
- 2-Hydroxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (CAS 1816937-59-3)
- Liraglutide-d8 Tetratrifluoroacetate (CAS 204656-20-2 (non-labelled, free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com