Haloperidol CAS 52-86-8
| CAS No. | 52-86-8 |
| Molecular Formula | C21H23ClFNO2 |
| Molecular Weight | 375.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Haloperidol (CAS 52-86-8), a certified reference material (molecular formula C21H23ClFNO2, MW 375.86 g/mol) for analytical method development and quality control.
Based on its molecular formula C21H23ClFNO2, Haloperidol contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 375.86 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C21H23ClFNO2 |
| Molecular Weight | 375.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Haloperidol Standards
- Haloperidol EP Impurity B (CAS 1391052-53-1)
- Haloperidol Impurity 15 (CAS CATO-C4X-146115)
- Haloperidol-d4 (CAS 1189986-59-1)
- Haloperidol Impurity 22 (CAS 660844-75-7)
- Haloperidol impurity 25 (CAS 150214-94-1)
- Haloperidol Impurity 9 (CAS 148406-51-3)
- trans-Haloperidol N-Oxide (CAS 150214-93-0)
- Haloperidol Impurity 39 (CAS 52669-92-8)
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