Mesna EP Impurity B CAS 1391053-66-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.1391053-66-9
Molecular FormulaC4H10N4O3S2
Molecular Weight226.28 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Mesna EP Impurity B CAS 1391053-66-9 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

As a process- or degradation-related impurity, Mesna EP Impurity B (CAS 1391053-66-9, C4H10N4O3S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Mesna EP Impurity B (C4H10N4O3S2) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC4H10N4O3S2
Molecular Weight226.28 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1991
Nitrogen Atoms4
Sulfur Atoms2

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