Mesna impurity 8 CAS 74304-26-0
| CAS No. | 74304-26-0 |
| Molecular Formula | C4H9ClO3S |
| Molecular Weight | 172.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Mesna impurity 8 (CAS 74304-26-0), a pharmacopoeial impurity reference standard (molecular formula C4H9ClO3S, MW 172.63 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Mesna impurity 8 (C4H9ClO3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 0.0, corresponding to approximately 0 ring(s) or double-bond equivalent(s). With a molecular weight of 172.63 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H9ClO3S |
| Molecular Weight | 172.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Mesna Standards
- Mesna Impurity 6 (CAS CATO-C4X-16926)
- Mesna EP Impurity C (CAS 69536-71-6)
- Mesna Related Compound A (2-(Acetylthio)ethane-1-sulfonic acid, potassium salt, crystal adduct with potassium chloride) (1392818) (CAS 2820170-85-0)
- Mesna EP Impurity A (CAS 25985-57-3)
- Mesna EP Impurity B (CAS 1391053-66-9)
- Mesna Impurity 3 (CAS 1823982-49-5)
- Mesna Impurity 7 (CAS CATO-C4X-16927)
- Mesna EP Impurity E (CAS 1391054-56-0)
Recommended Standards
- (E)-3-Thiophen-2-yl-acryloyl chloride 28424-61-5 F2146-0397 (CAS 28424-61-5)
- Ethyl 2-chloroethyl sulfonate (CAS 25372-93-4)
- S-(4-chlorophenyl) methanethioate (CAS 27064-05-7)
- 2-Amino-2-(5-chlorothiophen-2-yl)acetonitrile (CAS 1015434-52-2)
- Carteolol Impurity 29 (CAS 23674-56-8)
- Deucravacitinib Impurity 5 (CAS CATO-C4X-31385)
- Mirabegron EP Impurity F (CAS 223673-34-5)
- Ethyl 5,6-dimethoxy-1H-indazole-3-carboxylate (CAS 29281-06-9)
- 5,6-Diethyl-3-hydroxypyrazine-2-carboxamide (CAS 181284-16-2)
- tert-Butyl N-{5-hydroxybicyclo[2.2.1]heptan-2-yl}carbamate (CAS 1242273-72-8)
- tert-Butyl rac-(1R,2S,6R,7S)-4,10-diazatricyclo[5.2.1.0~2,6~]decane-10-carboxylate hydrochloride (CAS 1820580-15-1)
- N-(2,4,5-Trimethoxybenzyl)-3-pentanamine hydrobromide (CAS 1609402-77-8)
- Quercetinsulfonicacid (CAS 25512-46-3)
- Renin Inhibitor Peptide (CAS 50410-01-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com