Raltegravir EP Impurity H CAS 1391918-18-5
| CAS No. | 1391918-18-5 |
| Molecular Formula | C34H36F2N8O8 |
| Molecular Weight | 722.70 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Raltegravir EP Impurity H under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Raltegravir EP Impurity H (CAS 1391918-18-5, C34H36F2N8O8) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Raltegravir EP Impurity H (C34H36F2N8O8) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 20.0, corresponding to approximately 20 ring(s) or double-bond equivalent(s). With a molecular weight of 722.70 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C34H36F2N8O8 |
| Molecular Weight | 722.70 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Raltegravir Standards
- Raltegravir Glucuronide (CAS 952654-62-5)
- Raltegravir EP Impurity F (CAS 2138805-56-6)
- Raltegravir-d3 Potassium Salt (CAS 1246816-98-7)
- Raltegravir Impurity 9 (CAS 518048-02-7)
- Raltegravir EP Impurity C (CAS 1391918-17-4)
- Raltegravir Impurity15 (CAS 519028-33-2)
- Raltegravir -D6 (CAS 1100750-98-8)
- Raltegravir (CAS 518048-05-0)
Recommended Standards
- Etoposide EP Impurity F (CAS CATO-C4X-20246)
- Cefpirome Impurity 25 (CAS CATO-C4X-120725)
- Etoposide Impurity 40 (CAS CATO-C4X-202440)
- Cefpirome Impurity 43 (CAS CATO-C4X-120743)
- Ixazomib Impurity 71 (CAS 2920604-29-9)
- Pemetrexed Impurity 10 (CAS 151864-81-2)
- Dapoxetine Impurity 56 (CAS 2245197-07-1 (free base))
- 6-Ethyl-7-hydroxy-3-phenyl-2-(trifluoromethyl)-4h-chromen-4-one (CAS 105258-37-5)
- 3-(3,4-Dimethylphenoxy)pyrrolidine (CAS 946760-25-4)
- 5-Fluoropyrimidine-2,4-diamine (CAS 155-11-3)
- 2-(4-Ethoxyphenyl)-3-methylbutan-2-ol (CAS 1343670-56-3)
- Desmopressin EP Impurity E (CAS CATO-C4X-22155)
- Methyl 5-bromo-4-methoxythiophene-3-carboxylate (CAS 1353100-79-4)
- MCH-Gene-Overprinted-Polypeptide-14 (rat) (H-4746.0500) (CAS 182917-44-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com