Azilsartan Impurity 94 CAS 2839197-75-8
| CAS No. | 2839197-75-8 |
| Molecular Formula | C26H24N4O6 |
| Molecular Weight | 488.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 488.49 g/mol gives Azilsartan Impurity 94 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Azilsartan Impurity 94 (CAS 2839197-75-8, C26H24N4O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Azilsartan Impurity 94 (C26H24N4O6) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Azilsartan Impurity 94 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H24N4O6 |
| Molecular Weight | 488.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 4 |
Related Azilsartan Standards
- Azilsartan Impurity 51 (CAS 139481-38-2)
- Azilsartan Impurity 120 (CAS CATO-C4X-1096120)
- Azilsartan Impurity 119 (CAS CATO-C4X-1096119)
- Azilsartan Impurity 87 (CAS CATO-C4X-109687)
- Azilsartan Ethyl Ester Impurity (CAS 1403474-70-3)
- Azilsartan Impurity 39 (CAS CATO-C4X-109639)
- Azilsartan Impurity 93 (CAS 1800532-35-7)
- Azilsartan Impurity 126 (CAS 1604812-36-3)
Recommended Standards
- Thalidomide-O-PEG4-propargyl (CAS 2098799-77-8)
- Suc-Ala-Ala-Ala-AMC (CAS 73617-90-0)
- N-Mal-N-bis(PEG2-acid) (CAS 2110449-02-8)
- 2-((1R,4s)-5'-(4-amino-7,7-dimethyl-2-(trifluoromethyl)-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)-2',3'-dihydrospiro[cyclohexane-1,1'-inden]-4-yl)acetic acid (CAS 701232-94-2)
- Chlorpheniramine Impurity 15 (CAS 120244-82-8)
- Lesinurad impurity 16 (CAS CATO-C4X-147816)
- LCZ-696 Impurity 46 (CAS CATO-C4X-169646)
- 39739-07-6 KM3853 METHYL 2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)-3-HYDROXYPROPANOATE (CAS 39739-07-6)
- 1-(Propan-2-yloxy)cyclobutane-1-carboxylic acid (CAS 1856844-90-0)
- 5-Cyclopropoxy-N-methyl-4-(methylthio)nicotinamide (CAS 1243315-98-1)
- Pyrido[2,3-d]pyrimidin-7(8H)-one (CAS 258282-55-2)
- (S)-2-Cyclopropyl-1-(3-fluoro-4-methylphenyl)ethanamine (CAS 321840-50-0)
- 4,5,6,7-Tetrahydro-1-methyl-3-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine (CAS 794451-94-8)
- Hexapeptide-10 (CAS 146439-94-3)
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