Sildenafil Impurity 35 CAS 139756-01-7
| CAS No. | 139756-01-7 |
| Molecular Formula | C8H12N4O3 |
| Molecular Weight | 212.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Sildenafil Impurity 35 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Sildenafil Impurity 35 (CAS 139756-01-7) is a certified pharmaceutical impurity reference standard with the molecular formula C8H12N4O3 and a molecular weight of 212.21 g/mol.
The molecular framework of Sildenafil Impurity 35 (C8H12N4O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Sildenafil Impurity 35 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H12N4O3 |
| Molecular Weight | 212.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 4 |
Related Sildenafil Standards
- Sildenafil Impurity 59 (CAS 792969-85-8)
- Sildenafil Impurity N23 (CAS 247583-72-8)
- Sildenafil Impurity 41 (CAS 304435-83-4)
- Sildenafil RC 41 (CAS 222729-55-7)
- Sildenafil Impurity 36 (CAS 139756-00-6)
- Sildenafil RC 39 (CAS 1346605-36-4)
- Sildenafil Impurity 274 (CAS 1358966-40-1)
- Sildenafil Impurity 56 (CAS CATO-C4X-112856)
Recommended Standards
- Istradefylline Impurity 15 (CAS 89073-60-9)
- Fluconazole EP Impurity C (CAS 514222-44-7)
- Pentoxifylline Impurity 9 (CAS 1597448-45-7)
- N-butyl-4-nitro-1H-pyrazole-3-carboxamide (CAS 360573-39-3)
- Meglumine Impurity 12 (CAS CATO-C4X-214212)
- Mitiglinide Calcium Impurity 17 (CAS 70925-10-9)
- Nafamostat impurity 113 (CAS CATO-C4X-1332113)
- (2S)-N-Cbz-α,α-dimethyl-2-pyrrolidinemethanol (CAS 51207-68-2)
- (S)-N-Boc-1-fluoro-2-pentanamine (CAS 2006287-05-2)
- 11-Bromo-1,1,1-trifluoroundecane (CAS 86364-79-6)
- 4-Bromo-2-fluoro-5-isopropoxyaniline (CAS 84478-40-0)
- 3,4-Cibromobenzophenone (CAS 83699-51-8)
- 5-methylimidazo[1,2-a]pyrimidine-7-carboxylic acid (CAS 1030017-70-9)
- Neuropeptide Y (free acid) (human, rat) trifluoroacetate salt (CAS 99575-89-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com