Sildenafil Impurity N23 CAS 247583-72-8
| CAS No. | 247583-72-8 |
| Molecular Formula | C8H12N4O3 |
| Molecular Weight | 212.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Sildenafil Impurity N23 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Sildenafil Impurity N23 (CAS 247583-72-8) is a certified pharmaceutical impurity reference standard with the molecular formula C8H12N4O3 and a molecular weight of 212.21 g/mol.
Sildenafil Impurity N23 (C8H12N4O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C8H12N4O3 |
| Molecular Weight | 212.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
Related Sildenafil Standards
- Sildenafil Impurity 35 (CAS 139756-01-7)
- Sildenafil Impurity 59 (CAS 792969-85-8)
- Sildenafil Impurity 41 (CAS 304435-83-4)
- Sildenafil RC 41 (CAS 222729-55-7)
- Sildenafil Impurity 36 (CAS 139756-00-6)
- Sildenafil RC 39 (CAS 1346605-36-4)
- Sildenafil Impurity 274 (CAS 1358966-40-1)
- Sildenafil Impurity 56 (CAS CATO-C4X-112856)
Recommended Standards
- Niraparib Impurity 44 (CAS 1789348-02-2)
- H-Gly-His-OH (CAS 2489-13-6)
- Pentoxifylline Impurity 9 (CAS 1597448-45-7)
- H-His-Gly-OH (CAS 2578-58-7)
- Ivabradine Impurity 41 (CAS CATO-C4X-111941)
- Palbociclib Impurity 70 (CAS 1883672-48-7)
- Selexipag Impurity 46 (CAS 42042-66-0)
- 4-((5-Fluoropyridin-3-yl)sulfonyl)morpholine (CAS 1455879-07-8)
- 2,6-Diiodo-7H-purine (CAS 98027-95-3)
- Hexadecyl Sulfide (CAS 3312-77-4)
- 1-(3-Chloro-4-methylphenyl)-5-(4-methylbenzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione (CAS 537020-89-6)
- Epinephrine /Adrenaline Impurity 139 (CAS CATO-C4X-1849139)
- n-(4-Cyanophenyl)-3-iodobenzamide (CAS 349632-65-1)
- Semaglutide impurity 47 (CAS CATO-C4X-222647)
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