Azilsartan Impurity 7 CAS 1397836-49-5
| CAS No. | 1397836-49-5 |
| Molecular Formula | C24H22N4O4 |
| Molecular Weight | 430.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 430.46 g/mol gives Azilsartan Impurity 7 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Azilsartan Impurity 7 (CAS 1397836-49-5, C24H22N4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Azilsartan Impurity 7 (C24H22N4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Azilsartan Impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H22N4O4 |
| Molecular Weight | 430.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 4 |
Related Azilsartan Standards
- Azilsartan Impurity 175 (CAS CATO-C4X-1096175)
- Azilsartan Impurity 3 (CAS CATO-C4X-10963)
- Azilsartan Impurity 32 (CAS CATO-C4X-109632)
- Azilsartan Impurity N2 (CAS 1675221-59-6)
- Azilsartan Impurity 5 (CAS 147404-76-0)
- Azilsartan Impurity 118 (CAS CATO-C4X-1096118)
- Azilsartan Impurity 14 (CAS 1442400-68-1)
- Azilsartan Impurity 108 (CAS 2378769-58-3)
Recommended Standards
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- rel-(4R,6S)-2-Isopropyl-4,6-dimethyl-1,3,2-dioxaborinane (CAS 88062-10-6)
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- (4-(4-(Tert-butoxycarbonyl)piperazine-1-carbonyl)-3-fluorophenyl)boronic acid (CAS 1704069-67-9)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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