Amlodipine Impurity 59 CAS 140171-49-9
| CAS No. | 140171-49-9 |
| Molecular Formula | C29H29ClN2O7 |
| Molecular Weight | 553.00 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Amlodipine Impurity 59 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 553.00 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Amlodipine Impurity 59 (CAS 140171-49-9, C29H29ClN2O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Amlodipine Impurity 59 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C29H29ClN2O7 |
| Molecular Weight | 553.00 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amlodipine Standards
- Amlodipine Impurity 137 (CAS CATO-C4X-1095137)
- Amlodipine Impurity 119 (CAS CATO-C4X-1095119)
- Amlodipine Impurity 151 (CAS CATO-C4X-1095151)
- Amlodipine Impurity 54 (CAS CATO-C4X-109554)
- Amlodipine Besylate EP Impurity H (CAS 318465-73-5)
- Amlodipine impurity 130 (CAS CATO-C4X-1095130)
- Amlodipine Impurity 90 (CAS CATO-C4X-109590)
- Amlodipine Impurity 140 (CAS CATO-C4X-1095140)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com