Amlodipine Impurity 140 CAS CATO-C4X-1095140
| CAS No. | CATO-C4X-1095140 |
| Molecular Formula | C26H35ClN2O8 |
| Molecular Weight | 539.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Amlodipine Impurity 140 (CAS CATO-C4X-1095140) is a certified pharmaceutical impurity reference standard with the molecular formula C26H35ClN2O8 and a molecular weight of 539.02 g/mol.
Amlodipine Impurity 140 (C26H35ClN2O8) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Amlodipine Impurity 140 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H35ClN2O8 |
| Molecular Weight | 539.02 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amlodipine Standards
- Amlodipine Besylate EP Impurity A (CAS 88150-62-3)
- Amlodipine Impurity 135 (CAS CATO-C4X-1095135)
- Amlodipine Impurity 100 (CAS CATO-C4X-1095100)
- Amlodipine impurity 130 (CAS CATO-C4X-1095130)
- Amlodipine Impurity 90 (CAS CATO-C4X-109590)
- Amlodipine Impurity 36 (CAS 331258-36-7)
- Amlodipine Impurity 54 (CAS CATO-C4X-109554)
- Amlodipine Impurity 132 (CAS CATO-C4X-1095132)
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