Paliperidone Impurity 32 CAS 1404053-61-7
| CAS No. | 1404053-61-7 |
| Molecular Formula | C38H55FN4O4 |
| Molecular Weight | 650.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Paliperidone Impurity 32 (CAS 1404053-61-7, C38H55FN4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Paliperidone Impurity 32 (C38H55FN4O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Paliperidone Impurity 32 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C38H55FN4O4 |
| Molecular Weight | 650.87 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Paliperidone Standards
- Paliperidone Impurity 127 (CAS CATO-C4X-1724127)
- Paliperidone Impurity 131 (CAS CATO-C4X-1724131)
- Paliperidone Impurity 18 (CAS CATO-C4X-172418)
- Paliperidone Impurity 74 (CAS CATO-C4X-172474)
- Paliperidone impurity 146 (CAS CATO-C4X-1724146)
- Paliperidone Impurity 39 (CAS CATO-C4X-1724139)
- Paliperidone Impurity 38 (CAS CATO-C4X-1724138)
- Paliperidone Palmitate (CAS 199739-10-1)
Recommended Standards
- Atrasentan Impurity 46 (CAS 1059043-91-2)
- Atrasentan Impurity 51 (CAS 1059056-97-1)
- Bazedoxifene Acetate Impurity 7 (CAS 198480-21-6)
- Atrasentan Impurity 64 (CAS 1140456-20-7)
- Abrocitinib Impurity 38 (CAS CATO-C4X-288438)
- Venetoclax Impurity 90 (CAS CATO-C4X-249590)
- Tramadol EP Impurity C HCl (CAS 192834-41-1)
- 5-(((4,6-Dimethylpyrimidin-2-yl)thio)methyl)furan-2-carboxylic acid (CAS 438622-94-7)
- 1-[2-[(1-carboxy-3-phenylpropyl)amino]-1-oxopropyl]octahydro-1H-Indole-2-carboxylic acid racemic (CAS 83601-86-9)
- 3-(2,5-Difluorophenyl)propanenitrile (CAS 1057676-35-3)
- 2-(3,4-Dihydro-2h-1-benzopyran-4-yl)ethan-1-amine (CAS 1225814-82-3)
- 3-Iodo-5-(phenylthio)-1H-pyrrolo[2,3-b]pyridine (CAS 923583-56-6)
- Strontium 2-hydroxypropanoate (CAS 29870-99-3)
- Semaglutide Impurity 185 (CAS CATO-C4X-2226185)
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