Venetoclax Impurity 90 CAS CATO-C4X-249590
| CAS No. | CATO-C4X-249590 |
| Molecular Formula | C12H17N3O5S |
| Molecular Weight | 315.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 315.35 g/mol gives Venetoclax Impurity 90 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Venetoclax Impurity 90 (CAS CATO-C4X-249590, C12H17N3O5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Venetoclax Impurity 90 (C12H17N3O5S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 315.35 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H17N3O5S |
| Molecular Weight | 315.35 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Venetoclax Standards
- Venetoclax Impurity 1 (CAS 1228779-96-1)
- Venetoclax Impurity 102 (CAS CATO-C4X-2495102)
- Venetoclax Impurity 103 (CAS CATO-C4X-2495103)
- Venetoclax Impurity 117 (CAS CATO-C4X-2495117)
- Venetoclax Impurity 123 (CAS CATO-C4X-2495123)
- Venetoclax Impurity 136 (CAS CATO-C4X-2495136)
- Venetoclax Impurity 138 (CAS CATO-C4X-2495138)
- Venetoclax Impurity 133 (CAS CATO-C4X-2495133)
Recommended Standards
- Oxfendazole (CAS 53716-50-0)
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- 1-[4-(Ethylsulfonyl)-2-fluorophenyl]piperidine-3-carboxylic acid (CAS 1020722-14-8)
- 1-Methyl-4-[3-methyl-4-(propan-2-yl)phenyl]-3-(trifluoromethyl)-4,5-dihydro-1H-1,2,4-triazole-5-thione (CAS 1022692-91-6)
- Opicapone impurity 17 (CAS CATO-C4X-240417)
- Etoricoxib Impurity 78 (CAS 99055-63-7)
- Atogepant Impurity 5 (CAS CATO-C4X-32855)
- 2,2,2-trifluoroethyl N-(4,5-dimethyl-1,3-oxazol-2-yl)carbamate (CAS 1423024-90-1)
- Methyl 3-amino-3-(3-chloro-2-methylphenyl)propanoate (CAS 1823212-22-1)
- N-(3-chloro-4-(1H-pyrrol-1-yl)phenyl)-3-nitrobenzamide (CAS 383146-13-2)
- Ethyl 8-(4-hexylphenyl)-8-oxooctanoate (CAS 898757-36-3)
- 4-Chloro-7-fluoro-2-iodoquinazoline (CAS 1379357-83-1)
- 2-(2-Oxa-6-azaspiro[3.3]heptan-6-yl)ethanamine oxalate (CAS 1956354-52-1)
- Heptapeptide-6 (CAS CATO-CPTD788823)
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