5-Ethyl-3-(4-fluorophenyl)-1,2-oxazole-4-carboxylic acid CAS 1407074-26-3
| CAS No. | 1407074-26-3 |
| Molecular Formula | C12H10FNO3 |
| Molecular Weight | 235.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Ethyl-3-(4-fluorophenyl)-1,2-oxazole-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-Ethyl-3-(4-fluorophenyl)-1,2-oxazole-4-carboxylic acid (CAS 1407074-26-3) is a high-purity analytical reference standard with the molecular formula C12H10FNO3 and a molecular weight of 235.21 g/mol.
Structurally, 5-Ethyl-3-(4-fluorophenyl)-1,2-oxazole-4-carboxylic acid (C12H10FNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 235.21 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H10FNO3 |
| Molecular Weight | 235.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 5-Ethyl-1-(4-fluorophenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1017470-82-4)
- 5-Ethyl-1-(3-fluorophenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1094311-25-7)
- Ethyl 5-(2-Fluorophenyl)isoxazole-3-carboxylate (CAS 1126636-56-3)
- Methyl 1-(2-fluorophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate (CAS 1147207-80-4)
- 5-Ethyl-1-(2-fluorophenyl)-1h-1,2,4-triazole-3-carboxylic acid (CAS 1154370-83-8)
- [2-(4-Fluorophenyl)-4-methyl-1,3-oxazol-5-yl]acetic acid (CAS 1172370-81-8)
- 1-[2-(2-fluorophenyl)-2-oxoethyl]pyrrolidine-2,5-dione (CAS 1258652-22-0)
- Ethyl 5-(2-fluorophenyl)oxazole-4-carboxylate (CAS 127919-29-3)
Recommended Standards
- 3-(3-Fluoro-4-methylphenyl)-5-methylisoxazole-4-carboxylic acid (CAS 1407003-58-0)
- Methyl 5-(4-fluorophenyl)-2-methyloxazole-4-carboxylate (CAS 1407998-08-6)
- 2-(5-Amino-3-(4-fluorophenyl)-1h-pyrazol-1-yl)acetic acid (CAS 1405343-85-2)
- Ethyl 1-(5-fluoropyridin-2-yl)-1H-pyrazole-3-carboxylate (CAS 1410040-38-8)
- 3-(1-Methyl-5-oxo-2-thioxoimidazolidin-4-yl)propanamide (CAS 1968-37-2)
- 1-Vinyl-1H-benzo[d][1,2,3]triazole (CAS 2764-84-3)
- 3-(Ethoxycarbonyl)-5-hydroxybenzoic acid (CAS 95640-51-0)
- (1S,2S)-1,2-bis(4-bromophenyl)ethane-1,2-diamine (CAS 821766-66-9)
- 5-Bromo-7-fluoro-2,3-dihydrobenzofuran-3-amine (CAS 1156991-76-2)
- Etoricoxib impurity 54 (CAS 646459-47-4)
- (5-Bromothiophen-2-yl)(cyclopropyl)methanone (CAS 1216229-49-0)
- Captopril EP Impurity O (CAS CATO-C4X-119023)
- 3,5-Diamino-N-carbamothioyl-6-chloropyrazine-2-carboxamide (CAS 30478-39-8)
- Tau Peptide (307-321) trifluoroacetate salt (CAS 330456-50-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com