Calcitriol Impurity 14 CAS 140710-98-1
| CAS No. | 140710-98-1 |
| Molecular Formula | C39H72O3Si2 |
| Molecular Weight | 645.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Calcitriol Impurity 14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Calcitriol Impurity 14 (CAS 140710-98-1, C39H72O3Si2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Calcitriol Impurity 14 is typically off-white to pale yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 645.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C39H72O3Si2 |
| Molecular Weight | 645.16 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
Related Calcitriol Standards
- Calcitriol Impurity 17 (CAS 1883417-56-8)
- Calcitriol Impurity 8 (CAS 140710-96-9)
- Calcitriol impurity 39 (CAS 161885-78-5)
- Calcitriol Impurity 13 (CAS 169900-32-7)
- Calcitriol Impurity 18 (CAS 147125-21-1)
- Calcitriol Impurity 19 (CAS CATO-C4X-151019)
- Calcitriol Impurity 20 (CAS CATO-C4X-151020)
- Calcitriol Impurity 24 (CAS CATO-C4X-151024)
Recommended Standards
- (Z)-tetracos-15-en-1-yl (Z)-icos-11-enoate (CAS 872411-99-9)
- Lapaquistat Acetate (CAS 189060-13-7)
- Ceftazidime impurity 120 (CAS CATO-C4X-1212120)
- 26,27-Didesmethyl-1,3-(tert-butyldimethylsilyl) (5Z)-Calcitriol 24-Carboxylic Acid Methyl Ester (CAS 145372-43-6)
- Entacapone Impurity 57 (CAS CATO-C4X-162957)
- Clarithromycin EP Impurity I (CAS 118058-74-5)
- Gemcitabine Impurity 32 (CAS 122111-01-7)
- 1-Cyclopentyl-3-(pyridin-4-yl)propan-2-amine (CAS 1248386-43-7)
- Ceftriaxone Impurity 28 (CAS CATO-C4X-116328)
- Medroxy Progesterone-1,4-diene 17-Acetate (CAS 151-68-8)
- 1-Methylpiperidin-3-yl 1H-imidazole-1-carboxylate (CAS 811448-34-7)
- Methyl 4-(3,5-difluorophenyl)-3-methylbenzoate (CAS 2140327-06-4)
- 1-(2-(Pyridin-2-yl)pyrrolidin-1-yl)ethan-1-one (CAS 402937-53-5)
- Peptide Impurity 28 (CAS 1350456-64-2)
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