Entacapone Impurity 57 CAS CATO-C4X-162957
| CAS No. | CATO-C4X-162957 |
| Molecular Formula | C9H6N2O4 |
| Molecular Weight | 206.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 206.15 g/mol gives Entacapone Impurity 57 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Entacapone Impurity 57 (CAS CATO-C4X-162957) is a certified pharmaceutical impurity reference standard with the molecular formula C9H6N2O4 and a molecular weight of 206.15 g/mol.
Entacapone Impurity 57 (C9H6N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6N2O4 |
| Molecular Weight | 206.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Entacapone Standards
- Entacapone impurity 39 (CAS CATO-C4X-162939)
- Entacapone EP Impurity E (CAS 7659-29-2)
- Entacapone impurity 48 (CAS 89942-87-0)
- Entacapone Impurity 24 (CAS 4097-63-6)
- Entacapone Impurity 25 (CAS 6635-20-7)
- Entacapone Impurity 28 (CAS 2450-26-2)
- Entacapone Impurity 29 (CAS 2454-72-0)
- Entacapone Impurity 31 (CAS 80547-69-9)
Recommended Standards
- Vitamin Impurity 48 (CAS CATO-C4X-177948)
- (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid 71183-66-9 CHEBI:15607 (CAS 71183-66-9)
- Sodium Cromoglicate Impurity 13 (CAS 53878-47-0)
- (5,7-Dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)acetic acid 1644AE 36239-67-5 C9H6N2O4 (CAS 36239-67-5)
- Rebamipide Impurity 11 (CAS 4876-10-2)
- Lumefantrine Impurity N1 (CAS 2170653-95-7 (free base))
- Azilsartan Impurity 92 (CAS 1417576-01-2)
- N-(4-methoxyphenyl)-1-phenylcyclopentane-1-carboxamide (CAS 332392-06-0)
- O-Hippuryl-L-b-phenyllactic acid . sodium salt (M-1495.0005) (CAS 390394-56-6)
- Dipentamethylenethiuram Tetrasulfide (CAS 120-54-7)
- 2-Chloro-1-(5-chloro-3-fluoropyridin-2-yl)ethan-1-one (CAS 1374652-34-2)
- 5-Cyanopentanoic acid (CAS 5264-33-5)
- tert-Butyl (2-((tert-butoxycarbonyl)amino)ethyl)(2-hydroxyethyl)carbamate (CAS 200283-08-5)
- (D-Tyr1,N-Me-Phe3)-Neuropeptide FF (H-4752.0001) (CAS 145274-93-7)
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