Gemcitabine Impurity 32 CAS 122111-01-7
| CAS No. | 122111-01-7 |
| Molecular Formula | C19H14F2O6 |
| Molecular Weight | 376.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Gemcitabine Impurity 32 (CAS 122111-01-7, C19H14F2O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Gemcitabine Impurity 32 (C19H14F2O6) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 376.31 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Gemcitabine Impurity 32 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H14F2O6 |
| Molecular Weight | 376.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Gemcitabine Standards
- Gemcitabine Impurity 10 (CAS 1217452-91-9)
- Gemcitabine Impurity 17 (CAS 197452-15-6)
- Gemcitabine Impurity 29 (CAS 122111-02-8)
- Gemcitabine Impurity 16 (CAS 1173824-58-2)
- Gemcitabine Impurity 11 (CAS 143157-25-9)
- Gemcitabine Impurity 9 (CAS 143157-22-6)
- Gemcitabine Impurity 31 (CAS 142816-70-4)
- Gemcitabine Impurity 5 (CAS 2174019-90-8)
Recommended Standards
- 5,7-Disulfonaphthalene-1,4-dicarboxylic acid (CAS 1267804-17-0)
- 3',4',5,7-Tetrahydroxy 3,6,8-trimethoxyflavone (CAS 61451-85-2)
- 4,4-Bis(4-hydroxy-3-nitrophenyl)pentanoic acid (CAS 14601-82-2)
- ß-D-Glucopyranuronic acid methyl ester (CAS 533934-74-6)
- Domperidone Impurity 7 (CAS 53786-44-0)
- Rimegepant Impurity 14 (CAS 1397526-07-6)
- Cholic Acid Impurity 49 (CAS 691519-36-4)
- 4-Octyne (CAS 1942-45-6)
- Ethyl 2-amino-4-(4-butoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate (CAS 383410-62-6)
- 3-((tert-Butoxycarbonyl)amino)benzofuran-2-carboxylic acid (CAS 1035609-35-8)
- N-[2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-pyridyl]cyclopentanecarboxamide (CAS 2246873-46-9)
- Flunarizine Impurity 12 (CAS 88172-16-1)
- 8-fluoro-2,3,4,5-tetrahydro-1,4-benzoxazepine (CAS 844648-13-1)
- Des-Pro-Pro-Tirzepatide (CAS CATO-CPTD788696)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com