tert-Butyl (2S)-4,4-difluoro-2-[(methylamino)methyl]pyrrolidine-1-carboxylate CAS 1407997-82-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1407997-82-3
Molecular FormulaC11H20F2N2O2
Molecular Weight250.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl (2S)-4,4-difluoro-2-[(methylamino)methyl]pyrrolidine-1-carboxylate CAS 1407997-82-3 chemical structure

Description

The occurrence of tert-Butyl (2S)-4,4-difluoro-2-[(methylamino)methyl]pyrrolidine-1-carboxylate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

tert-Butyl (2S)-4,4-difluoro-2-[(methylamino)methyl]pyrrolidine-1-carboxylate (CAS 1407997-82-3), molecular formula C11H20F2N2O2 and molecular weight 250.29 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, tert-Butyl (2S)-4,4-difluoro-2-[(methylamino)methyl]pyrrolidine-1-carboxylate (C11H20F2N2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 250.29 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H20F2N2O2
Molecular Weight250.29 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1991
Halogen ContentF-containing
Nitrogen Atoms2

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