2-(((Tert-butyldiphenylsilyl)oxy)methyl)cyclobutan-1-one CAS 140852-32-0
| CAS No. | 140852-32-0 |
| Molecular Formula | C21H26O2Si |
| Molecular Weight | 338.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2-(((Tert-butyldiphenylsilyl)oxy)methyl)cyclobutan-1-one (CAS 140852-32-0), a certified reference material (molecular formula C21H26O2Si, MW 338.52 g/mol) for analytical method development and quality control.
The molecular framework of 2-(((Tert-butyldiphenylsilyl)oxy)methyl)cyclobutan-1-one (C21H26O2Si) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 2-(((Tert-butyldiphenylsilyl)oxy)methyl)cyclobutan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H26O2Si |
| Molecular Weight | 338.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
Related Tert Standards
- 4-((tert-Butyldiphenylsilyl)oxy)piperidine (CAS 396091-35-3)
- 4-((tert-Butyldiphenylsilyl)oxy)dihydrofuran-3(2H)-one (CAS 467249-22-5)
- (1-(((tert-Butyldiphenylsilyl)oxy)methyl)cyclopropyl)methanol (CAS 441785-04-2)
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- 2-(2-((tert-Butyldiphenylsilyl)oxy)ethoxy)ethanol (CAS 160052-24-4)
- 1-[(tert-Butyldiphenylsilyl)oxy]-3-chloro-2-propanone (CAS 1956332-66-3)
- 4-((tert-Butyldiphenylsilyl)oxy)butan-2-ol (CAS 114079-44-6)
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Recommended Standards
- (S)-2-(((tert-butyldiphenylsilyl)oxy)methyl)cyclobutan-1-one (CAS 135253-29-1)
- (6-Oxabicyclo[3.1.0]hexan-3-yloxy)(tert-butyl)diphenylsilane (CAS 1616434-79-7)
- (3|A,20R)-Pregn-5-ene-3,17,20-triol-d4 (CAS 105078-93-1)
- (1R,2S)-2-(((tert-Butyldiphenylsilyl)oxy)methyl)cyclopropane-1-carbaldehyde (CAS 251444-03-8)
- 10-Methoxy-3,4,5,6-tetrahydro-2H-1,5-benzoxazocine (CAS 938459-13-3)
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- 4-(3-Iodophenoxy)piperidine (CAS 946726-33-6)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
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