Racecadotril Diacid Impurity CAS 141437-87-8
| CAS No. | 141437-87-8 |
| Molecular Formula | C20H22O4S2 |
| Molecular Weight | 390.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Racecadotril Diacid Impurity.
As a process- or degradation-related impurity, Racecadotril Diacid Impurity (CAS 141437-87-8, C20H22O4S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Racecadotril Diacid Impurity (C20H22O4S2) contains a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H22O4S2 |
| Molecular Weight | 390.52 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Sulfur Atoms | 2 |
Related Racecadotril Standards
- Racecadotril-D5 (CAS 1246815-11-1)
- Racecadotril (CAS 81110-73-8)
- Racecadotril Impurity 25 (CAS CATO-C4X-110625)
- Racecadotril Impurity 16 (CAS 2173396-73-9)
- Racecadotril Impurity 14 (CAS CATO-C4X-110614)
- Racecadotril Impurity 29 (CAS CATO-C4X-110629)
- Racecadotril Impurity 28 (CAS CATO-C4X-110628)
- Racecadotril EP Impurity G (CAS 81110-69-2)
Recommended Standards
- Solifenacin Impurity 38 (CAS 605696-10-4)
- Rosuvastatin Impurity 173 (CAS CATO-C4X-1169173)
- tert-Butyl 6-benzyl-2,3,4,5,6,6a-hexahydroindeno[1,2-b:3,2-b']dipyrrole-1(10bH)-carboxylate (CAS 2621395-77-3)
- Rosuvastatin Impurity 174 (CAS CATO-C4X-1169174)
- Macitentan Impurity 47 (CAS CATO-C4X-117547)
- Argatroban Impurity 122 (CAS CATO-C4X-1007122)
- Brivudine Impurity 10 (CAS 69304-48-9)
- N-(4-(2-Methyl-4-oxoquinazolin-3(4H)-yl)phenyl)methanesulfonamide (CAS 38501-68-7)
- Benzhydryl 3-oxobutanoate (CAS 39567-17-4)
- 3-(tert-Butoxy)-5-cyclopropoxy-2-nitropyridine (CAS 1243284-24-3)
- 6-Amino-5-chloro-4-(difluoromethyl)nicotinic acid (CAS 1806831-23-1)
- 2-(3,3-Difluoropyrrolidin-1-yl)-3-nitropyridine (CAS 1779124-29-6)
- (2-Chlorothiazol-5-yl)methyl (4-nitrophenyl)carbamate (CAS 672949-95-0)
- Peptide 439 (CAS CATO-CPTD788439)
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