Fasudil Impurity 48 CAS 141543-63-7

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.141543-63-7
Molecular FormulaC13H15N3O2S
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Fasudil Impurity 48 CAS 141543-63-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 313.80 g/mol gives Fasudil Impurity 48 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Fasudil Impurity 48 (CAS 141543-63-7) is a certified pharmaceutical impurity reference standard with the molecular formula C13H15N3O2SHCl and a molecular weight of 313.80 g/mol.

The molecular framework of Fasudil Impurity 48 (C13H15N3O2SHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Fasudil Impurity 48 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H15N3O2S HCl
Molecular Weight313.80 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1997
Halogen ContentCl-containing
Nitrogen Atoms3
Sulfur Atoms1

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