N-(4-chlorobenzyl)-4-((2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)benzamide CAS 339025-02-4
| CAS No. | 339025-02-4 |
| Molecular Formula | C21H16ClF3N2O2 |
| Molecular Weight | 420.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 420.81 g/mol gives N-(4-chlorobenzyl)-4-((2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)benzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(4-chlorobenzyl)-4-((2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)benzamide (CAS 339025-02-4), molecular formula C21H16ClF3N2O2 and molecular weight 420.81 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(4-chlorobenzyl)-4-((2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)benzamide (C21H16ClF3N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(4-chlorobenzyl)-4-((2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H16ClF3N2O2 |
| Molecular Weight | 420.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- N-(2-chlorobenzyl)-4-((2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)benzamide (CAS 339025-44-4)
- N-(3-chlorobenzyl)-2-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carbonyl)benzamide (CAS 861212-84-2)
- 1-(4-Chlorobenzyl)-4-(3-(2,4-dichlorophenyl)-1H-pyrazol-5-yl)piperidine (CAS 321848-35-5)
- 1-(4-Chlorobenzyl)-3'-phenylspiro[indoline-3,2'-thiazolidine]-2,4'-dione (CAS 338419-04-8)
- 3-(2-((3-Chlorobenzyl)thio)pyrimidin-4-yl)-1-(p-tolyl)pyridazin-4(1H)-one (CAS 478077-68-8)
- N-(2-Chlorobenzyl)-2-((4-ethyl-5-(3-methoxy-1-methyl-1H-pyrazol-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 1014095-15-8)
- N-(4-chlorobenzyl)-1-(3,4-dichlorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 338754-40-8)
- 2-(5-(4-((4-Chlorobenzyl)oxy)benzylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid (CAS 303134-98-7)
Recommended Standards
- N-(3-chloro-2-methylphenyl)-4-((2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)benzamide (CAS 339025-34-2)
- N-[(4-Chlorophenyl)methyl]-2-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide (CAS 338782-35-7)
- N-benzyl-1-(4-chlorobenzyl)-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide (CAS 551921-71-2)
- 5-Chloro-N-methyl-6-oxo-N-phenyl-1-(3-(trifluoromethyl)benzyl)-1,6-dihydropyridine-3-carboxamide (CAS 400087-48-1)
- 4-(4-Methoxyphenoxy)-3-(trifluoromethyl)aniline (CAS 87294-18-6)
- 2-Chloromethyl-4-(2,4-dichlorophenyl)-6-methylpyridine-3,5-dicarboxylicacid 5-benzyl 3-ethylester (CAS 915296-81-0)
- 2-Amino-4-(3,4-dimethoxyphenyl)thiophene-3-carbonitrile (CAS 884497-31-8)
- 7-methyl-1H,2H,3H,4H-pyrido[2,3-b]pyrazine (CAS 1378818-55-3)
- (2R,3R,5R,6S)-2-Hydroxy-6-methyltetrahydro-2H-pyran-3,5-diyl dibenzoate (CAS 104768-13-0)
- Bosentan USP Related Compound A (CAS 150727-06-3)
- 2-(Trifluoromethoxy)benzoic acid (CAS 150436-84-3)
- Ertugliflozin impurity 57 (CAS CATO-C4X-301157)
- Canagliflozin Impurity 112 (CAS 1132832-76-8)
- Macrophage Inhibitory Peptide (CAS 41961-56-2)
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