5-((3-Methyl-[1,2,4]triazolo[4,3-a]pyrazin-8-yl)oxy)nicotinic acid CAS 1421662-49-8
| CAS No. | 1421662-49-8 |
| Molecular Formula | C12H9N5O3 |
| Molecular Weight | 271.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-((3-Methyl-[1,2,4]triazolo[4,3-a]pyrazin-8-yl)oxy)nicotinic acid.
CATO supplies 5-((3-Methyl-[1,2,4]triazolo[4,3-a]pyrazin-8-yl)oxy)nicotinic acid (CAS 1421662-49-8), a certified reference material (molecular formula C12H9N5O3, MW 271.23 g/mol) for analytical method development and quality control.
The molecular framework of 5-((3-Methyl-[1,2,4]triazolo[4,3-a]pyrazin-8-yl)oxy)nicotinic acid (C12H9N5O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-((3-Methyl-[1,2,4]triazolo[4,3-a]pyrazin-8-yl)oxy)nicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9N5O3 |
| Molecular Weight | 271.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 5 |
Related Methyl Standards
- 2-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-1-(5-fluoro-6-methylpyridin-2-yl)ethanone (CAS 1132610-47-9)
- 6-Methyl[1,2,4]triazolo[4,3-b]pyridazin-8-yl 4-fluorobenzenecarboxylate (CAS 478046-02-5)
- N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)-2-chlorobenzamide (CAS 338406-09-0)
- 2-({3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}oxy)ethan-1-amine (CAS 1204296-83-2)
- 2-((5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)amino)benzoic acid (CAS 392739-38-7)
- 4-((5-Methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)amino)benzoic acid (CAS 330850-44-7)
- 6-Methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl 4-methylbenzoate (CAS 478046-06-9)
- 4-(2H-[1,2,3]Triazolo[4,5-b]pyridin-2-yl)-N,N-diethylaniline (CAS 106671-77-6)
Recommended Standards
- (2S,3S)-2-((tert-Butoxycarbonyl)amino)-4,4,4-trifluoro-3-methylbutanoic acid (CAS 1414348-95-0)
- N-(3-Methylisoxazol-5-yl)-6-(1H-1,2,4-triazol-1-yl)pyridazine-3-carboxamide (CAS 1448124-39-7)
- (2R,3S)-2-((tert-Butoxycarbonyl)amino)-4,4,4-trifluoro-3-methylbutanoic acid (CAS 1414348-94-9)
- N-(5-Methylisoxazol-3-yl)-6-(1H-1,2,4-triazol-1-yl)pyridazine-3-carboxamide (CAS 1448130-88-8)
- 2-(4-Bromo-1-methyl-1H-pyrazol-3-yl)acetonitrile (CAS 1310379-44-2)
- 3-(Chloromethyl)-5-phenyl-1,2,4-oxadiazole (CAS 1201-68-9)
- 2-(5-Bromo-1-methyl-1H-imidazol-4-yl)ethan-1-amine dihydrobromide (CAS 2137887-35-3)
- 1-Phenylquinolin-4(1H)-one (CAS 40695-01-0)
- Methyl 3-Chloro-4-morpholinobenzoate (CAS 1314406-49-9)
- 6-ethynyl-2,2-difluoro-spiro[2.5]octane (CAS 2306272-57-9)
- 3-(2-Chloro-3-methoxyphenyl)propanoic acid (CAS 853331-56-3)
- 8-(sec-Butylthio)-7-hexyl-3-methyl-3,7-dihydro-1H-purine-2,6-dione (CAS 332033-50-8)
- 1,3-Dichloro-2-iodo-4-nitrobenzene (CAS 1803809-06-4)
- Liraglutide Impurity 20 TFA Salt (CAS CATO-C4X-199220)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com