3-Chloro-5-methylisothiazole CAS 14217-67-5
| CAS No. | 14217-67-5 |
| Molecular Formula | C4H4ClNS |
| Molecular Weight | 133.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-Chloro-5-methylisothiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 3-Chloro-5-methylisothiazole (CAS 14217-67-5), a certified reference material (molecular formula C4H4ClNS, MW 133.60 g/mol) for analytical method development and quality control.
Structurally, 3-Chloro-5-methylisothiazole (C4H4ClNS) contains a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 133.60 g/mol, it falls into the low-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C4H4ClNS |
| Molecular Weight | 133.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-Chloro-4-methylisothiazole (CAS 1072-56-6)
- 2-Chloro-1,3-dimethyl-1H-imidazol-3-ium chloride (CAS 125376-11-6)
- 5-Chloro-4-methylthiazole (CAS 125402-79-1)
- 2-Chloro-4-methylthiazole (CAS 26847-01-8)
- 2-Chloro-5-methylthiazole (CAS 33342-65-3)
- 4-Chloro-3-methylisothiazole (CAS 930-43-8)
- 5-Chloro-2-methyl-1,3-thiazole (CAS 57268-15-2)
- 5-Chloro-2-thiophenamine (CAS 63806-78-0)
Recommended Standards
- 14214-31-4 Isothiocyanic acid, 2-chloroallyl ester 1-Propene, 2-chloro-3-isothiocyanato- (9CI) 2-Chlor-3-isothiocyanato-1-propene 0-04-00-00219 (Beilstein Handbook Reference) BRN 1748580 beta-Chloroallyl isothiocyanate 2-Chloroallyl isothiocyanate 2-Chloro-3-isothiocyanato-1-propene EC 604-275-3 (CAS 14214-31-4)
- 4-Chlorothiophen-2-amine (CAS 1427372-77-7)
- 5-(Chloromethyl)isothiazole (CAS 1710-68-5)
- 3-(Chloromethyl)isothiazole (CAS 1246549-42-7)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(3,5-dimethylphenyl)-1H-pyrrole-2-sulfonamide (CAS 321433-65-2)
- 4-(1H-pyrazol-4-yl)butan-1-amine (CAS 84302-89-6)
- 1-(3-Methyl-4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)piperidine-3-carboxylic acid (CAS 1708428-20-9)
- 3-Chloro-6-(trifluoromethyl)-1H-indazole (CAS 1000341-24-1)
- 6-Methyl-2h-spiro[benzofuran-3,4'-piperidine] hydrochloride (CAS 1992956-36-1)
- 3-amino-1-(pyrazin-2-yl)propan-1-ol (CAS 1501680-98-3)
- 3-(6-Bromo-1H-benzoimidazol-2-ylsulfanyl)-propionic acid (CAS 312616-15-2)
- Guaiacol Propionate (CAS 7598-60-9)
- Benzyl (2-(cyclohexylamino)-2-oxo-1-phenylethyl)carbamate (CAS 17922-88-2)
- Des-Tyr10-Tirzepatide (CAS CATO-CPTD788680)
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