2-Chloro-5-methylthiazole CAS 33342-65-3
| CAS No. | 33342-65-3 |
| Molecular Formula | C4H4ClNS |
| Molecular Weight | 133.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-Chloro-5-methylthiazole (C4H4ClNS) contains a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 133.60 g/mol, it falls into the low-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-Chloro-5-methylthiazole (CAS 33342-65-3), molecular formula C4H4ClNS and molecular weight 133.60 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-5-methylthiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H4ClNS |
| Molecular Weight | 133.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-Chloro-4-methylisothiazole (CAS 1072-56-6)
- 2-Chloro-1,3-dimethyl-1H-imidazol-3-ium chloride (CAS 125376-11-6)
- 5-Chloro-4-methylthiazole (CAS 125402-79-1)
- 3-Chloro-5-methylisothiazole (CAS 14217-67-5)
- 2-Chloro-4-methylthiazole (CAS 26847-01-8)
- 4-Chloro-3-methylisothiazole (CAS 930-43-8)
- 5-Chloro-2-methyl-1,3-thiazole (CAS 57268-15-2)
- 5-Chloro-2-thiophenamine (CAS 63806-78-0)
Recommended Standards
- 3-Chlorothiophen-2-amine (CAS 491879-26-6)
- 5-(Chloromethyl)isothiazole (CAS 1710-68-5)
- 4-(Chloromethyl)isothiazole (CAS 89033-79-4)
- 4-Chlorothiophen-2-amine (CAS 1427372-77-7)
- ethyl 2,2-difluoro-3-(morpholin-4-yl)-3-oxopropanoate (CAS 1357625-59-2)
- (2,3-Dimethyl-6-(trifluoromethyl)imidazo[2,1-b]thiazol-5-yl)methanol (CAS 1823510-54-8)
- 2-(Chloromethyl)-6-cyano-4-(difluoromethyl)-3-hydroxypyridine (CAS 1807149-73-0)
- 1-(3,5-Dimethylbenzoyl)piperidine-2-carboxylic acid (CAS 1101193-09-2)
- 2-(2,4-Dichlorophenyl)morpholine (CAS 1097797-70-0)
- 4-(2-hydroxyethyl)-2,6-dimethoxyphenol (CAS 20824-45-7)
- 6-(2-Phenylethenyl)oxane-2,4-dione (CAS 57012-11-0)
- 3-Bromo-2-fluoro-5-(trifluoroacetamido)phenylboronic acid (CAS 2377608-69-8)
- Ethyl 4-chloro-2-((2,4-dichlorobenzyl)thio)pyrimidine-5-carboxylate (CAS 6944-75-8)
- (D-Trp32)-Neuropeptide Y (porcine) trifluoroacetate salt (CAS 153549-78-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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